• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Participation of Black Americans in Cancer Clinical Trials: Current Challenges and Proposed Solutions.美国黑人参与癌症临床试验:当前的挑战与解决方案建议。
JCO Oncol Pract. 2021 May;17(5):265-271. doi: 10.1200/OP.21.00001.
2
Using Critical Race Theory to Understand Trial Participation Among Black Individuals With Systemic Lupus Erythematosus: A Qualitative Study of Patients and Caregivers.运用批判种族理论理解系统性红斑狼疮黑人个体参与临床试验:患者和照护者的定性研究。
Arthritis Care Res (Hoboken). 2021 Oct;73(10):1387-1395. doi: 10.1002/acr.24635. Epub 2021 Sep 12.
3
Systemic racism: individuals and interactions, institutions and society.系统性种族主义:个体与互动、制度与社会。
Cogn Res Princ Implic. 2021 Dec 20;6(1):82. doi: 10.1186/s41235-021-00349-3.
4
Diversity, equity, and inclusion interventions to support admissions have had little benefit to Black students over past 20 years.多元化、公平和包容干预措施以支持招生,但在过去 20 年中对黑人学生几乎没有好处。
J Dent Educ. 2021 Apr;85(4):448-455. doi: 10.1002/jdd.12611. Epub 2021 Apr 7.
5
Enrollment of Black Participants in Pivotal Clinical Trials Supporting US Food and Drug Administration Approval of Chimeric Antigen Receptor-T Cell Therapy for Hematological Malignant Neoplasms.支持美国食品和药物管理局批准嵌合抗原受体 T 细胞疗法治疗血液恶性肿瘤的关键临床试验中纳入黑人参试者的情况。
JAMA Netw Open. 2022 Apr 1;5(4):e228161. doi: 10.1001/jamanetworkopen.2022.8161.
6
Rethinking the issue of reparations for Black Americans.重新思考美国黑人的赔偿问题。
Bioethics. 2022 Mar;36(3):235-242. doi: 10.1111/bioe.12954. Epub 2021 Sep 13.
7
Perceived stress following race-based discrimination at work is associated with hypertension in African-Americans. The metro Atlanta heart disease study, 1999-2001.工作中基于种族的歧视所带来的感知压力与非裔美国人的高血压有关。1999 - 2001年亚特兰大心脏病研究。
Soc Sci Med. 2004 Feb;58(3):449-61. doi: 10.1016/s0277-9536(03)00211-9.
8
Inclusion of black Americans in oncology clinical trials: the Louisiana State University Medical Center experience.美国黑人参与肿瘤学临床试验:路易斯安那州立大学医学中心的经验。
Am J Clin Oncol. 1999 Feb;22(1):18-21. doi: 10.1097/00000421-199902000-00005.
9
Gain versus loss-framed messaging and colorectal cancer screening among African Americans: A preliminary examination of perceived racism and culturally targeted dual messaging.得失框架信息传递与非裔美国人的结直肠癌筛查:对感知种族主义和文化针对性双重信息传递的初步考察。
Br J Health Psychol. 2016 May;21(2):249-67. doi: 10.1111/bjhp.12160. Epub 2015 Sep 1.
10
Fundamental causes of barriers to participation in Alzheimer's clinical research among African Americans.非裔美国人参与阿尔茨海默病临床研究障碍的根本原因。
Ethn Health. 2021 May;26(4):585-599. doi: 10.1080/13557858.2018.1539222. Epub 2018 Oct 30.

引用本文的文献

1
Innovative Development of Research Engagement Manual: Strategies to Enhance Recruitment and Retention of Black Individuals in Clinical Trials for Substance Use Disorders.《研究参与手册的创新发展:提高黑人个体参与物质使用障碍临床试验的招募与留存率的策略》
Health Equity. 2025 Aug 22;9(1):387-396. doi: 10.1177/24731242251362181. eCollection 2025.
2
"The more I know, the more you know" Using culturally responsive marketing strategies to develop tools that increase awareness about clinical trials among Black communities.“我知道得越多,你知道得越多”:运用具有文化适应性的营销策略来开发工具,以提高黑人社区对临床试验的认知度。
BMC Public Health. 2025 Sep 1;25(1):3003. doi: 10.1186/s12889-025-24194-x.
3
Bridging the gap: ctDNA, genomics, and equity in breast cancer care.弥合差距:循环肿瘤DNA、基因组学与乳腺癌护理的公平性
NPJ Breast Cancer. 2025 Aug 16;11(1):92. doi: 10.1038/s41523-025-00811-1.
4
Callback time preference for prescreening visits among Black residents in the Boston area: findings from two randomized controlled trials.波士顿地区黑人居民预筛查就诊的回访时间偏好:两项随机对照试验的结果
Trials. 2025 Aug 8;26(1):281. doi: 10.1186/s13063-025-08998-1.
5
A Formative Evaluation of Interventions to Enhance Clinical Trial Diversity Guided by the Socioecological Model.以社会生态模型为指导的增强临床试验多样性干预措施的形成性评估。
Cancers (Basel). 2025 Jul 9;17(14):2282. doi: 10.3390/cancers17142282.
6
Engagement in cancer clinical trials among a nationally representative cancer survivor sample: Motivators, barriers and opportunities for improvement.全国代表性癌症幸存者样本中参与癌症临床试验的情况:动机、障碍及改进机会。
Tumori. 2025 Aug;111(4):349-359. doi: 10.1177/03008916251347175. Epub 2025 Jun 12.
7
Community perspectives on cancer and cancer research: findings from listening sessions with diverse groups in Philadelphia.社区对癌症及癌症研究的看法:来自费城不同群体座谈会的结果
Discov Public Health. 2025;22(1):329. doi: 10.1186/s12982-025-00713-4. Epub 2025 Jun 9.
8
Exceptional Long-term Response to Immunotherapy in an African American Man With -Mutated Metastatic Lung Adenocarcinoma.一名携带KRAS突变的转移性肺腺癌非裔美国男性对免疫疗法的长期显著反应。
J Investig Med High Impact Case Rep. 2025 Jan-Dec;13:23247096251346830. doi: 10.1177/23247096251346830. Epub 2025 May 31.
9
Evaluating patient diversity in early phase clinical trials in Australia through a prospective multicenter nonrandomized cohort study.通过一项前瞻性多中心非随机队列研究评估澳大利亚早期临床试验中的患者多样性。
JNCI Cancer Spectr. 2025 Mar 3;9(2). doi: 10.1093/jncics/pkaf035.
10
Racial Differences in ctDNA Profiles, Targeted Therapy Use, and Outcomes in Metastatic Breast Cancer.转移性乳腺癌中循环肿瘤DNA(ctDNA)特征、靶向治疗应用及预后的种族差异
JAMA Netw Open. 2025 Feb 3;8(2):e2461899. doi: 10.1001/jamanetworkopen.2024.61899.

本文引用的文献

1
Assessment of Outcomes Associated With the Use of Newly Approved Oncology Drugs in Medicare Beneficiaries.评估在医疗保险受益人群中使用新批准的肿瘤药物相关的结局。
JAMA Netw Open. 2021 Feb 1;4(2):e210030. doi: 10.1001/jamanetworkopen.2021.0030.
2
Digitizing clinical trials.临床试验数字化。
NPJ Digit Med. 2020 Jul 31;3:101. doi: 10.1038/s41746-020-0302-y. eCollection 2020.
3
A Time to Dig Deeper and Take Meaningful Action.是时候深入挖掘并采取有意义的行动了。
J Clin Oncol. 2020 Oct 10;38(29):3361-3362. doi: 10.1200/JCO.20.02158. Epub 2020 Aug 12.
4
Cancer Disparities and Health Equity: A Policy Statement From the American Society of Clinical Oncology.癌症差异与健康公平:美国临床肿瘤学会政策声明。
J Clin Oncol. 2020 Oct 10;38(29):3439-3448. doi: 10.1200/JCO.20.00642. Epub 2020 Aug 12.
5
Representativeness of Black Patients in Cancer Clinical Trials Sponsored by the National Cancer Institute Compared With Pharmaceutical Companies.与制药公司赞助的癌症临床试验相比,美国国立癌症研究所赞助的癌症临床试验中黑人患者的代表性。
JNCI Cancer Spectr. 2020 Apr 24;4(4):pkaa034. doi: 10.1093/jncics/pkaa034. eCollection 2020 Aug.
6
Participation of African American Persons in Clinical Trials Supporting U.S. Food and Drug Administration Approval of Cancer Drugs.非裔美国人参与支持美国食品药品监督管理局批准癌症药物的临床试验情况。
Ann Intern Med. 2020 Aug 18;173(4):320-322. doi: 10.7326/M20-0410. Epub 2020 Jun 23.
7
Cancer statistics, 2020.癌症统计数据,2020 年。
CA Cancer J Clin. 2020 Jan;70(1):7-30. doi: 10.3322/caac.21590. Epub 2020 Jan 8.
8
Association of Race and Socioeconomic Status With Colorectal Cancer Screening, Colorectal Cancer Risk, and Mortality in Southern US Adults.种族和社会经济地位与美国南部成年人结直肠癌筛查、结直肠癌风险和死亡率的关联。
JAMA Netw Open. 2019 Dec 2;2(12):e1917995. doi: 10.1001/jamanetworkopen.2019.17995.
9
Disparity of Race Reporting and Representation in Clinical Trials Leading to Cancer Drug Approvals From 2008 to 2018.2008年至2018年导致癌症药物获批的临床试验中种族报告与代表性的差异
JAMA Oncol. 2019 Oct 1;5(10):e191870. doi: 10.1001/jamaoncol.2019.1870. Epub 2019 Oct 10.
10
With equal access, African American patients have superior survival compared to white patients with multiple myeloma: a VA study.一项退伍军人事务部的研究表明,在接受同等治疗的情况下,非裔美国骨髓瘤患者比白人患者的生存率更高。
Blood. 2019 Jun 13;133(24):2615-2618. doi: 10.1182/blood.2019000406. Epub 2019 Apr 19.

美国黑人参与癌症临床试验:当前的挑战与解决方案建议。

Participation of Black Americans in Cancer Clinical Trials: Current Challenges and Proposed Solutions.

机构信息

Department of Medicine, Lahey Hospital and Medical Center, Burlington, MA.

Department of Hematology and Oncology, Baylor College of Medicine, Houston, TX.

出版信息

JCO Oncol Pract. 2021 May;17(5):265-271. doi: 10.1200/OP.21.00001.

DOI:10.1200/OP.21.00001
PMID:33974816
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8258017/
Abstract

Low participation of Black Americans in cancer clinical trials is a well-established predicament. Many factors resulted in this current dilemma with racism being the fundamental unit. Here, we discuss some current challenges and proposed solutions to help in increasing the enrollment of Black Americans in cancer clinical trials. We suggest implementing the least acceptable race-specific percentage as a new bar that registrational clinical trials need to pass before cancer drugs approval. Clinical trials will continue to draw the future of cancer therapeutics in which we believe that a prompt improvement of Black Americans participation is warranted.

摘要

美国黑人参与癌症临床试验的比例低是一个既定的困境。许多因素导致了目前的困境,其中种族主义是根本原因。在这里,我们讨论了一些当前的挑战和提出的解决方案,以帮助增加美国黑人参与癌症临床试验的人数。我们建议实施最不可接受的特定种族百分比作为新的标准,注册临床试验需要在批准癌症药物之前通过这个标准。临床试验将继续为癌症治疗的未来绘制蓝图,我们相信有必要迅速提高美国黑人的参与度。