Ornowska Sylwia, Chojnowski Marek, Felis-Giemza Anna, Dudek Łukasz, Olesińska Marzena
Department of Systemic Connective Tissue Diseases, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.
Medical University of Warsaw, Poland.
Reumatologia. 2021;59(2):115-120. doi: 10.5114/reum.2021.105457. Epub 2021 Apr 27.
Mixed connective tissue disease (MCTD) is a complex entity, which incorporates features of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis (SSc) and polymyositis/dermatomyositis (PM/DM). Nailfold videocapillaroscopy (NVC) is a simple, safe and non-invasive technique of capillary vessel assessment, allowing for qualitative and quantitative assessment of microcirculation. NVC plays a pivotal role in the diagnostic algorithm of connective tissue diseases, especially in systemic sclerosis (SSc). Numerous studies have shown a correlation between organ involvement and disease progression in SSc. In the current literature, there are limited data on relationship between NVC and organ involvement in MCTD patients. In the present article the relevant literature describing NVC examination in patients with MCTD and comparisons with some clinical situations are discussed.
混合性结缔组织病（MCTD）是一种复杂的疾病，它兼具系统性红斑狼疮（SLE）、类风湿关节炎（RA）、系统性硬化症（SSc）和多发性肌炎/皮肌炎（PM/DM）的特征。甲襞微血管镜检查（NVC）是一种简单、安全且无创的毛细血管评估技术，可对微循环进行定性和定量评估。NVC在结缔组织病的诊断流程中起着关键作用，尤其是在系统性硬化症（SSc）中。大量研究表明，SSc中的器官受累与疾病进展之间存在关联。在当前文献中，关于MCTD患者NVC与器官受累之间关系的数据有限。在本文中，将讨论描述MCTD患者NVC检查以及与一些临床情况比较的相关文献。
