Jiang Yongquan, Cao Wanxin, Luo Yuanbo, Xu Ji, Li Ying, Li Jiping
Department of Otolaryngology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Case Rep Oncol. 2021 Mar 22;14(1):568-572. doi: 10.1159/000510361. eCollection 2021 Jan-Apr.
Laryngeal squamous cell carcinoma (LSCC) is the most common malignant head and neck cancer, with a 40% recurrence rate in the first 3 years after radical treatment. Recurrence of LSCC mostly comprises lymphogenous metastasis, hematogenic metastasis, and locoregional recurrence, while LSCC seeding is rarest: there are only 4 cases reported in PubMed, and none of them is one of subcutaneous seeding. We report a case with post-surgery subcutaneous seeding of LSCC. The final biopsy demonstrated that the subcutaneous seeding of the LSCC was 2 cm away from the primary lesion, with no recurrent foci observed in the larynx and tracheostoma and little relation to the primary lesion. Thus, we drew the conclusion that LSCC surgeries should stick to the principle of the non-tumor technique to prevent subcutaneous seeding.
喉鳞状细胞癌（LSCC）是最常见的头颈部恶性肿瘤，根治性治疗后3年内复发率为40%。LSCC复发主要包括淋巴转移、血行转移和局部区域复发，而LSCC种植转移最为罕见：PubMed上仅报道了4例，且均非皮下种植转移。我们报告1例LSCC术后皮下种植转移病例。最终活检显示，LSCC皮下种植转移灶距原发灶2 cm，喉和气管造口处未观察到复发灶，且与原发灶关系不大。因此，我们得出结论，LSCC手术应坚持无瘤技术原则以预防皮下种植转移。
