Singh Bhupesh, Sharma Sourabh, Dadia Suchit, Bharti Neha, Bharti Sudhank
Bharti Eye Foundation and Hospital, New Delhi, India.
Case Rep Ophthalmol. 2021 Apr 12;12(1):208-213. doi: 10.1159/000513345. eCollection 2021 Jan-Apr.
Marfan syndrome (MFS) is known to cause significant refractive error. Treatment options are limited in this condition for correcting refractive error. Clear lens exchange is done in these cases, but complication rates are high. Loss of accommodation is another concern in these young adults. We report toric phakic intraocular lens (pIOL) implantation in improving the uncorrected visual acuity (UCVA) in a known case of MFS with lens coloboma. A 22-year-old female patient with MFS with inferior lens coloboma underwent bilateral toric pIOL implantation in the same sitting. Pre- and post-operative UCVA and best-corrected visual acuity were assessed. Central and peripheral vaulting of the pIOL in relation to the natural lens was also assessed. UCVA improved from 20/500 to 20/20 in the right and 20/550-20/20 in the left eye. Marked central vaulting with partial peripheral vaulting was achieved. There were no post-operative complications. Phakic IOL implantation surgery could be an effective approach to achieve excellent uncorrected refractive outcome in patients with MFS to treat high myopia.
众所周知，马凡综合征（MFS）会导致明显的屈光不正。在这种情况下，矫正屈光不正的治疗选择有限。对于这些病例会进行透明晶状体置换，但并发症发生率很高。在这些年轻成年人中，调节功能丧失是另一个问题。我们报告了在一例已知患有晶状体缺损的马凡综合征患者中，植入散光型有晶状体眼人工晶状体（pIOL）以提高未矫正视力（UCVA）的情况。一名患有马凡综合征且伴有下方晶状体缺损的22岁女性患者在同一次手术中接受了双侧散光型pIOL植入。评估了术前和术后的UCVA以及最佳矫正视力。还评估了pIOL相对于自然晶状体的中央和周边拱高。右眼的UCVA从20/500提高到20/20，左眼从20/550提高到20/20。实现了明显的中央拱高和部分周边拱高。术后无并发症。有晶状体眼人工晶状体植入手术可能是一种有效的方法，可使马凡综合征患者获得良好的未矫正屈光效果，以治疗高度近视。
