Amoore J N, Rudy Y
Department of Biomedical Engineering, UCT Medical School, Observatory, Cape, South Africa.
J Electrocardiol. 1988 Apr;21(2):154-60. doi: 10.1016/s0022-0736(88)80011-6.
Two previously published models of the electrocardiogram are compared and evaluated to determine the causes and nature of the relationship between variations in ventricular volumes and surface potential. Both models included a relatively high conductivity spherical heart in a spherical torso, but in one the source was a single dipole, while in the other the source was a double-layer spherical cap. Volume conductor effects (that is the change in electrical conductivity of the torso associated with ventricular volume changes) caused a decrease in surface potential with increase in ventricular volume. Changes in position of the heart and of the strength of the activation wavefront with increases in volume may explain the increase in surface potential with ventricular volume observed in experimental studies.
对之前发表的两种心电图模型进行了比较和评估，以确定心室容积变化与体表电位之间关系的原因和本质。两种模型均包括一个位于球形躯干中的电导率相对较高的球形心脏，但其中一个模型的源是单个偶极子，而另一个模型的源是双层球形帽。容积导体效应（即与心室容积变化相关的躯干电导率变化）导致体表电位随心室容积增加而降低。心脏位置的变化以及随着容积增加激活波前强度的变化，可能解释了实验研究中观察到的体表电位随心室容积增加的现象。
