Complejo Asistencial Universitario de León, León, Spain.
Faculty of Health Sciences, University of León, León, Spain.
Methods Mol Biol. 2021;2296:423-439. doi: 10.1007/978-1-0716-1358-0_25.
Antibiotic resistance is not only a European or American problem: it is a global crisis. The emergence of resistance to multiple antimicrobial agents has become a major threat to public health. The main objective of the institution's antimicrobial policy is to adapt the effective treatment to each patient, with a minimum of complications, avoid adverse reactions, control the development and spread of strains of resistant microorganisms as well as reduce hospital costs whenever possible. World Health Organization published a global list of priority pathogens of antibiotic-resistant bacteria to help prioritize research and development of new and effective antibiotic treatments. We must take into account the risk factors related to multiresistance, as well as factors that favor horizontal and vertical transmission. The need to prioritize implementation of these global strategies is complex and involves a lot of effort and valuable time; this point favors the rapid development resistance.
它是一个全球性的危机。对多种抗菌药物的耐药性的出现已成为对公众健康的主要威胁。该机构抗菌政策的主要目标是为每个患者提供有效的治疗,尽量减少并发症,避免不良反应,控制耐药微生物菌株的发展和传播,并尽可能降低医院成本。世界卫生组织发布了一份全球抗生素耐药细菌优先病原体清单,以帮助确定新的有效抗生素治疗方法的研究和开发的优先级。我们必须考虑与多耐药性相关的危险因素,以及有利于水平和垂直传播的因素。优先实施这些全球战略的必要性是复杂的,需要付出大量的努力和宝贵的时间;这一点有利于耐药性的迅速发展。