Akpinar Guleser, Demir Mehmet C, Sultanoglu Hasan, Unlu Elif N, Oksuz Sukru
Clin Lab. 2021 May 1;67(5). doi: 10.7754/Clin.Lab.2020.200929.
Clinical findings of COVID-19 have been observed with a wide spectrum ranging from asymptomatic disease and mild upper respiratory tract infection to severe viral pneumonia resulting in mortality. While clinical symptoms present in some COVID-19 patients, others have been incidentally identified. The objective of this study was to examine the clinical and laboratory features of patients diagnosed with COVID-19 who were symptomatic or had atypical symptoms and to make a contribution to the literature.
Patients with the likelihood of having COVID-19 pneumonia were evaluated with RT-PCR samples, other laboratory tests, and chest computed tomography.
There were significant differences between these groups in terms of age, dyspnea, saturation, and comor-bidities including hypertension [HT] in 19 patients, cerebrovascular events [CVE] that were classified as other diseases in two patients (intracranial mass in one patient and Alzheimer's disease in one patient), and CRP and platelet counts (PLT) among the laboratory parameters (for all p < 0.05).
Atypical symptoms have increased due to the progression of the outbreak. Infected people with atypical symptoms can act as sources of the infection. Therefore, the epidemiological history of these patients should be sought in detail, and individuals with atypical symptoms in society should be identified as soon as possible in order to control the spreading of the disease.
新型冠状病毒肺炎（COVID-19）的临床症状表现多样，从无症状感染、轻度上呼吸道感染到导致死亡的严重病毒性肺炎。一些COVID-19患者有临床症状，而另一些则是偶然发现。本研究的目的是检查有症状或非典型症状的COVID-19确诊患者的临床和实验室特征，并为文献做出贡献。
对疑似患有COVID-19肺炎的患者进行逆转录聚合酶链反应（RT-PCR）样本检测、其他实验室检查以及胸部计算机断层扫描评估。
这些组在年龄、呼吸困难、血氧饱和度以及合并症方面存在显著差异，合并症包括19例高血压患者、2例被归类为其他疾病的脑血管事件患者（1例颅内肿块患者和1例阿尔茨海默病患者），实验室参数中的C反应蛋白（CRP）和血小板计数（PLT）（所有p<0.05）。
随着疫情的发展，非典型症状有所增加。有非典型症状的感染者可能成为传染源。因此，应详细询问这些患者的流行病学史，并尽快识别社会上有非典型症状的个体，以控制疾病传播。
