Alaei Ravin, Shen Carl, Chan Brian J, Martin James
Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Division of Ophthalmology, Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
Ocul Immunol Inflamm. 2022 Oct-Nov;30(7-8):1564-1567. doi: 10.1080/09273948.2021.1906909. Epub 2021 May 12.
To report a case of Purtscher-like retinopathy secondary to acute pancreatitis caused by medication-induced calcium-alkali syndrome in a pregnant woman.
Case report.
A 39-year-old 23-week pregnant patient complained of visual disturbances during admission for acute pancreatitis precipitated by calcium-alkali syndrome. History revealed the acute ingestion of over 2,400 mg of elemental calcium from over the counter medication in the background of longstanding use. Visual acuity was counting fingers at 1 foot bilaterally. Posterior segment exam revealed Purtscher-flecken in the posterior pole with scattered dot hemorrhages. Optical coherence tomography (OCT) revealed inner retinal thickening and increased hyper-reflectivity. OCT angiography demonstrated loss of flow primarily in the superficial capillary plexuses. The patient was diagnosed with Purtscher-like retinopathy and observed. Two months follow up revealed resolution of the funduscopic findings and visual acuity improved minimally to 20/200 in the right eye and counting fingers in the left eye.
Common over the counter medication can potentiate a calcium-alkali syndrome capable of causing a Purtscher-like retinopathy.
报告一例因药物性钙碱综合征继发急性胰腺炎导致的类Purtscher视网膜病变的孕妇病例。
病例报告。
一名39岁、孕23周的患者因钙碱综合征引发急性胰腺炎入院,诉有视觉障碍。病史显示,长期用药的背景下,患者过量服用了超过2400毫克的非处方药物中的元素钙。双眼视力均为1英尺处数指。眼底检查发现后极部有Purtscher样病灶及散在点状出血。光学相干断层扫描(OCT)显示视网膜内层增厚,高反射率增加。OCT血管造影显示主要在浅表毛细血管丛血流缺失。该患者被诊断为类Purtscher视网膜病变并进行观察。两个月的随访显示眼底检查结果消退,视力略有改善,右眼为20/200,左眼为数指。
常见的非处方药物可引发能导致类Purtscher视网膜病变的钙碱综合征。