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本文引用的文献

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A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis.抗生素与阑尾切除术治疗阑尾炎的随机对照试验。
N Engl J Med. 2020 Nov 12;383(20):1907-1919. doi: 10.1056/NEJMoa2014320. Epub 2020 Oct 5.
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Effect of SARS-CoV-2 on the Incidence of Appendicitis: The Role of Quarantine.严重急性呼吸综合征冠状病毒2(SARS-CoV-2)对阑尾炎发病率的影响:隔离的作用。
Pediatr Emerg Care. 2020 Aug;36(8):e482-e483. doi: 10.1097/PEC.0000000000002182.
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The management of adult appendicitis during the COVID-19 pandemic: an interim analysis of a UK cohort study.COVID-19 大流行期间成人阑尾炎的管理:一项英国队列研究的中期分析。
Tech Coloproctol. 2021 Apr;25(4):401-411. doi: 10.1007/s10151-020-02297-4. Epub 2020 Jul 15.
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Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study.围手术期 SARS-CoV-2 感染患者的死亡率和肺部并发症:一项国际队列研究。
Lancet. 2020 Jul 4;396(10243):27-38. doi: 10.1016/S0140-6736(20)31182-X. Epub 2020 May 29.
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Interpreting a covid-19 test result.解读新冠病毒检测结果。
BMJ. 2020 May 12;369:m1808. doi: 10.1136/bmj.m1808.
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COVID-19 patients presenting with afebrile acute abdominal pain.出现无发热性急性腹痛的新冠肺炎患者。
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Emergency Surgery in Suspected COVID-19 Patients With Acute Abdomen: Case Series and Perspectives.疑似新型冠状病毒肺炎合并急腹症患者的急诊手术:病例系列及观点
Ann Surg. 2020 Jul;272(1):e38-e39. doi: 10.1097/SLA.0000000000003961.
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Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines.急性阑尾炎的诊断和治疗:WSES 耶路撒冷指南 2020 年更新版。
World J Emerg Surg. 2020 Apr 15;15(1):27. doi: 10.1186/s13017-020-00306-3.
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Management of Uncomplicated Acute Appendicitis as Day Case Surgery: Can Outcomes of a Prospective Study Be Reproduced in Real Life?单纯性急性阑尾炎日间手术管理:前瞻性研究的结果能否在实际中再现?
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新冠疫情期间的阑尾炎:一家区综合医院的经验教训

Appendicitis during the COVID-19 pandemic: lessons learnt from a district general hospital.

作者信息

Pringle Heather C M, Donigiewicz Urszula, Bennett Melissa-Rose, Walker Eleanor, Fowler George E, Narang Sunil, Ball Susan, Bethune Robert M

机构信息

Royal Devon & Exeter Hospital, Exeter, EX2 5DW, Devon, UK.

University of Exeter Medical School, St. Luke's Campus, Heavitree Road, Exeter, EX1 2LU, Devon, UK.

出版信息

BMC Surg. 2021 May 12;21(1):242. doi: 10.1186/s12893-021-01231-1.

DOI:10.1186/s12893-021-01231-1
PMID:33980191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8114653/
Abstract

BACKGROUND

The COVID-19 pandemic dramatically influenced the delivery of healthcare. In line with the UK Royal Colleges' advice the management of acute appendicitis (AA) changed with greater consideration for non-operative management (NOM) or open appendicectomy when operative management (OM) was sought. We describe our experience of the presentation, management and outcomes for these patients to inform care for future viral pandemics.

METHODS

This retrospective, cohort study compared patients diagnosed with AA between March and July 2019 with those during the pandemic period of March to July 2020. Medical records were reviewed to obtain demographics, inflammatory markers, imaging, severity, management, histology, length of stay (LOS) and 90-day outcomes.

RESULTS

There were 149 and 125 patients in the 2019 and 2020 cohorts respectively. 14 patients (9.4%) had NOM in 2019 versus 31 (24.8%) in 2020 (p = 0.001). In the 2019 operative management (OM) group 125 patients (92.6%) had laparoscopic appendicectomy versus 65 (69.1%) in 2020. 59 patients (39.6%) had a CT in 2019 versus 70 (56%) in 2020. The median LOS was 4 days in 2019 and 3 days in 2020 (p = 0.03). Two patients in each year who received NOM had treatment failure (14.3% in 2019 and 6.5% in 2020). Three patients in 2019 who received OM had treatment failure (2.2%). Of 95 patients tested for COVID-19 all but one tested negative.

CONCLUSION

During the COVID-19 pandemic there was no observed increase in severity of AA, patients had a shorter LOS and were more likely to have imaging. NOM proportionally increased with no observed change in outcomes.

摘要

背景

新冠疫情对医疗服务的提供产生了巨大影响。根据英国皇家医学院的建议,急性阑尾炎(AA)的管理方式发生了变化,在寻求手术治疗(OM)时,对非手术治疗(NOM)或开放式阑尾切除术给予了更多考虑。我们描述了这些患者的临床表现、治疗及预后情况,以为未来应对病毒性大流行时的医疗护理提供参考。

方法

这项回顾性队列研究比较了2019年3月至7月与2020年3月至7月大流行期间诊断为AA的患者。查阅医疗记录以获取人口统计学信息、炎症标志物、影像学检查结果、病情严重程度、治疗方式、组织学检查结果、住院时间(LOS)和90天预后情况。

结果

2019年队列中有149例患者,2020年队列中有125例患者。2019年有14例患者(9.4%)接受了非手术治疗,2020年为31例(24.8%)(p = 0.001)。在2019年的手术治疗(OM)组中,125例患者(92.6%)接受了腹腔镜阑尾切除术,2020年为65例(69.1%)。2019年有59例患者(占39.6%)进行了CT检查,2020年为70例(占56%)。2019年的中位住院时间为4天,2020年为3天(p = 0.03)。每年接受非手术治疗的患者中有2例治疗失败(2019年为14.3%,2020年为6.5%)。2019年接受手术治疗的患者中有3例治疗失败(2.2%)。在接受新冠病毒检测的95例患者中,除1例以外其余均为阴性。

结论

在新冠疫情期间,未观察到急性阑尾炎病情严重程度增加,患者住院时间缩短,且更有可能接受影像学检查。非手术治疗比例相应增加,预后未观察到变化。