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1
A rare case of hypokalaemia and hypophosphataemia secondary to geophagia.一例罕见的因食土癖继发低钾血症和低磷血症的病例。
BMJ Case Rep. 2021 May 12;14(5):e239322. doi: 10.1136/bcr-2020-239322.
2
Hypokalemic myopathy in pregnancy caused by clay ingestion.
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Severe hypokalemia and hypophosphatemia presenting with carpopedal spasm associated with rhabdomyolysis.严重低钾血症和低磷血症伴手足痉挛及横纹肌溶解症。
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Severe hypercalcaemia and hypophosphataemia with an optimised preterm parenteral nutrition formulation in two epochs of differing phosphate supplementation.在两个不同磷酸盐补充阶段,采用优化的早产肠外营养配方时出现的严重高钙血症和低磷血症。
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引用本文的文献

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Hypokalaemia in pregnancy - Prevalence, underlying causes, and an approach to investigation.妊娠期低钾血症——患病率、潜在病因及调查方法
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2
The Association Between Pica and Iron-Deficiency Anemia: A Scoping Review.异食癖与缺铁性贫血之间的关联:一项范围综述
Cureus. 2023 Apr 20;15(4):e37904. doi: 10.7759/cureus.37904. eCollection 2023 Apr.

本文引用的文献

1
Do aluminium-based phosphate binders continue to have a role in contemporary nephrology practice?含铝的磷酸盐结合剂在当代肾脏病实践中是否仍有作用?
BMC Nephrol. 2011 May 13;12:20. doi: 10.1186/1471-2369-12-20.
2
Diagnosis of hypokalemia: a problem-solving approach to clinical cases.低钾血症的诊断:临床病例的解决方法
Iran J Kidney Dis. 2008 Jul;2(3):115-22.
3
Rhabdomyolysis: a review of clinical presentation, etiology, diagnosis, and management.横纹肌溶解症:临床表现、病因、诊断及管理综述
Pediatr Emerg Care. 2008 Apr;24(4):262-8. doi: 10.1097/PEC.0b013e31816bc7b7.
4
Clay Mineralogy: The clay mineral composition of soils and clays is providing an understanding of their properties.粘土矿物学:土壤和粘土的粘土矿物组成正在为了解它们的性质提供帮助。
Science. 1962 Mar 16;135(3507):890-8. doi: 10.1126/science.135.3507.890.
5
Glycosphingolipids modulate renal phosphate transport in potassium deficiency.糖鞘脂在钾缺乏时调节肾脏磷酸盐转运。
Kidney Int. 2001 Aug;60(2):694-704. doi: 10.1046/j.1523-1755.2001.060002694.x.
6
Total-body skeletal muscle mass: evaluation of 24-h urinary creatinine excretion by computerized axial tomography.全身骨骼肌质量:通过计算机断层扫描评估24小时尿肌酐排泄量。
Am J Clin Nutr. 1996 Jun;63(6):863-9. doi: 10.1093/ajcn/63.6.863.
7
Clay ingestion and iron deficiency anemia.摄入黏土与缺铁性贫血。
Ann Intern Med. 1982 Sep;97(3):456. doi: 10.7326/0003-4819-97-3-456_1.
8
Clay ingestion: a rare cause of hypokalemia.摄入黏土:低钾血症的罕见病因。
Ann Intern Med. 1982 Jul;97(1):65-6. doi: 10.7326/0003-4819-97-1-65.
9
Measurement of muscle mass in humans: validity of the 24-hour urinary creatinine method.人体肌肉质量的测量:24小时尿肌酐法的有效性
Am J Clin Nutr. 1983 Mar;37(3):478-94. doi: 10.1093/ajcn/37.3.478.
10
Pica in Turkey. II. Effect of clay upon iron absorption.
Am J Clin Nutr. 1968 Jan;21(1):78-86. doi: 10.1093/ajcn/21.1.78.

一例罕见的因食土癖继发低钾血症和低磷血症的病例。

A rare case of hypokalaemia and hypophosphataemia secondary to geophagia.

作者信息

Schmidt Charmaine, Oxley Oxland Jonathan, Freercks Robert

机构信息

Department of Internal Medicine, Livingstone Hospital, Port Elizabeth, South Africa.

Department of Medicine, Walter Sisulu University, Port Elizabeth, South Africa.

出版信息

BMJ Case Rep. 2021 May 12;14(5):e239322. doi: 10.1136/bcr-2020-239322.

DOI:10.1136/bcr-2020-239322
PMID:33980550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8118014/
Abstract

We report a case of severe hypokalaemia and moderate hypophosphataemia from clay ingestion. A 60-year-old woman presented with flaccid paralysis. Investigations revealed a serum potassium level of 1.8 mmol/L, phosphate level of 0.56 mmol/L and creatine kinase level of 30 747 IU/L. She had marked proximal and distal muscle weakness due to severe hypokalaemia and concurrent hypophosphataemia, which likely contributed to the onset of rhabdomyolysis. The patient subsequently admitted to significant pica, most likely secondary to an associated iron deficiency. We conclude that the ingested clay acted as a potassium and phosphate binder. Although we did not investigate the content of the clay in this case, it has been reported that clay can bind potassium in vitro and is rich in minerals such as aluminium that could play a role in the binding of phosphate, although the exact mechanism remains unclear. The patient recovered fully and outpatient follow-up at 6 months and again at 40 months confirmed no electrolyte abnormality, myopathy nor any further geophagia.

摘要

我们报告一例因摄入黏土导致严重低钾血症和中度低磷血症的病例。一名60岁女性出现弛缓性麻痹。检查发现血清钾水平为1.8 mmol/L,磷酸盐水平为0.56 mmol/L,肌酸激酶水平为30747 IU/L。由于严重低钾血症和并发低磷血症,她出现了明显的近端和远端肌肉无力,这可能导致了横纹肌溶解症的发生。患者随后承认有明显的异食癖,很可能继发于相关的缺铁。我们得出结论,摄入的黏土起到了钾和磷酸盐结合剂的作用。尽管在这个病例中我们没有研究黏土的成分,但据报道,黏土在体外可以结合钾,并且富含铝等矿物质,这些矿物质可能在磷酸盐的结合中起作用,尽管确切机制尚不清楚。患者完全康复,6个月和40个月的门诊随访证实没有电解质异常、肌病或任何进一步的食土癖。