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白内障手术后干眼指标的对比研究。

Comparative Study of Dry Eye Indices Following Cataract Surgery.

机构信息

Sagarmatha Choudhary Eye Hospital, Lahan, Siraha, Nepal.

出版信息

Nepal J Ophthalmol. 2021 Jan;13(25):104-111. doi: 10.3126/nepjoph.v13i1.29313.

DOI:10.3126/nepjoph.v13i1.29313
PMID:33981104
Abstract

BACKGROUND

This study aims to assess dry eye indices following cataract surgery.

MATERIALS AND METHODS

A single center descriptive and comparative study was performed. A total of 100 eyes of 100 cases fulfilling the inclusion criteria from 1st June 2017 to 30th May 2018 were enrolled. Out of 100 eyes, 50 eyes each went through manual small incision cataract surgery (MSICS) and phacoemulsification respectively. For objective analysis : schirmer 1 test(ST-I), tear breakup Time(TBUT) along with lissamine Green Surface Staining(LGSS) was performed on pre-operative day, 1st, 4th and 12th week respectively. Ocular Surface Disease Index (OSDI) was done for subjective analysis on pre-operative day and at 12th week.

RESULTS

The mean age of the patient was 53.66 ± 7.839 years with 34 (68%) being female in a small incision cataract surgery group. In the phacoemulsification group, mean age was 54.72 ± 7.985 years and 32 (64%) were female. On analyzing the objective dry eye indices: ST-I,TBUT and LGSS at 12thweek was 18.80 ± 7.393 mm, 11.30 ± 5.456 seconds and 1.62 ± 1.193 in Small incision cataract surgery group and 27.10 ± 6.326 mm, 16.60 ± 4.699 seconds and 0.38 ± 0.602 in Phacoemulsification group respectively which was statistically significant. (p< 0.001).

CONCLUSION

Regardless of the type of cataract surgery, dry eye disease is unavoidable affecting both tear quality and quantity postoperatively. In our study, phacoemulsification had lesser effect in dry eye indices than small incision cataract surgery.

摘要

背景

本研究旨在评估白内障手术后的干眼指标。

材料和方法

进行了一项单中心描述性和对照研究。共有 100 例符合纳入标准的患者(100 只眼)纳入研究,纳入时间为 2017 年 6 月 1 日至 2018 年 5 月 30 日。100 只眼中,50 只眼分别行手动小切口白内障手术(MSICS)和超声乳化白内障吸除术。客观分析:术前及术后第 1、4、12 周行 Schirmer 试验(ST-I)、泪膜破裂时间(TBUT)及丽丝胺绿染色(LGSS);主观分析行眼表疾病指数(OSDI),分别于术前和术后第 12 周进行。

结果

MSICS 组患者的平均年龄为 53.66 ± 7.839 岁,女性 34 例(68%);超声乳化白内障吸除术组患者的平均年龄为 54.72 ± 7.985 岁,女性 32 例(64%)。分析客观干眼指标:术后第 12 周时,MSICS 组的 ST-I、TBUT 和 LGSS 分别为 18.80 ± 7.393mm、11.30 ± 5.456 秒和 1.62 ± 1.193,超声乳化白内障吸除术组分别为 27.10 ± 6.326mm、16.60 ± 4.699 秒和 0.38 ± 0.602,差异均有统计学意义(p<0.001)。

结论

无论白内障手术类型如何,术后都会不可避免地出现泪液质量和数量的改变,即干眼。在本研究中,超声乳化白内障吸除术对干眼指标的影响小于手动小切口白内障手术。

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