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相对年龄对儿童心理健康的影响:一项对 9548393 名儿童和青少年的队列研究。

Effect of relative age on childhood mental health: A cohort of 9,548,393 children and adolescents.

机构信息

Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan.

Division of Psychiatry, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.

出版信息

Acta Psychiatr Scand. 2021 Aug;144(2):168-177. doi: 10.1111/acps.13327. Epub 2021 Jun 1.

DOI:10.1111/acps.13327
PMID:33982276
Abstract

BACKGROUND

The effect of relative age on the diagnoses of attention deficit hyperactivity disorder (ADHD), disruptive behavior disorder (DD), anxiety disorder, and depressive disorder and the prescription for ADHD and antidepressant medications remains unclear.

AIM

To clarify the impact of relative age in a school year with the diagnoses of ADHD, DD, anxiety disorder, and depressive disorder and the prescription for ADHD and antidepressant medications.

METHODS

The annual cutoff birthdate for entry to school in Taiwan is August 31. The Taiwan National Health Insurance Research Database was used to enroll 9,548,393 children and adolescents aged 3-17 years during the study period (September 1, 2001, to August 31, 2011). The Poisson regression model was performed to examine the likelihood of receiving diagnoses of ADHD, DD, anxiety disorder, and depressive disorder, as well as the prescription of ADHD and antidepressant medications among children born in August (the youngest) and September (the oldest).

RESULTS

Both boys and girls born in August had a higher risk of being diagnosed as having ADHD (odds ratio [OR] = boys: 1.65, girls: 1.80), DD (1.29, 1.45), anxiety disorder (1.49, 1.33), and depressive disorder (1.10, 1.10). Furthermore, children born in August were more likely to be prescribed ADHD medication (1.71, 1.72) and antidepressants (1.18, 1.09) compared with those born in September.

DISCUSSION

Relative age, as an indicator of neurocognitive maturity, is a critical factor for the likelihood of being diagnosed as having ADHD, DD, anxiety disorder, and depressive disorder among children and adolescents.

摘要

背景

相对年龄对注意力缺陷多动障碍(ADHD)、破坏性行为障碍(DD)、焦虑症和抑郁症的诊断以及 ADHD 和抗抑郁药物的处方的影响尚不清楚。

目的

阐明学年相对年龄对 ADHD、DD、焦虑症和抑郁症的诊断以及 ADHD 和抗抑郁药物的处方的影响。

方法

台湾入学的年度截止出生日期为 8 月 31 日。本研究使用台湾全民健康保险研究数据库,纳入了 2001 年 9 月 1 日至 2011 年 8 月 31 日期间 3-17 岁的 9548393 名儿童和青少年。采用泊松回归模型,分析 8 月(最小)和 9 月(最大)出生的儿童接受 ADHD、DD、焦虑症和抑郁症诊断以及 ADHD 和抗抑郁药物处方的可能性。

结果

8 月出生的男孩和女孩被诊断为 ADHD(优势比[OR]男孩:1.65,女孩:1.80)、DD(1.29,1.45)、焦虑症(1.49,1.33)和抑郁症(1.10,1.10)的风险更高。此外,与 9 月出生的儿童相比,8 月出生的儿童更有可能被开 ADHD 药物(1.71,1.72)和抗抑郁药(1.18,1.09)。

讨论

相对年龄作为神经认知成熟度的指标,是儿童和青少年被诊断为 ADHD、DD、焦虑症和抑郁症的可能性的关键因素。

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