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严重急性呼吸综合征冠状病毒2型所致的严重免疫性血小板减少性紫癜

SARS-CoV-2-Induced Severe Immune Thrombocytopenic Purpura.

作者信息

Gonze Aurelien, Hannesse Colin, Coppens Nathalie, Vellemans Helene, Maury Gisele

机构信息

Pneumology Department, Clinique Saint Luc, Rue Saint Luc 8, 5004 Namur, Belgium.

Hematology Department, Clinique Saint Luc, Rue Saint Luc 8, 5004 Namur, Belgium.

出版信息

J Med Cases. 2020 Jun;11(6):166-168. doi: 10.14740/jmc3481. Epub 2020 May 28.

Abstract

Hematologic changes are common in coronavirus infections, including lymphopenia and thrombocytopenia. Thrombocytopenia was frequent during the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 - 2003. The mechanisms involved in platelet deficiency are unclear. Many viruses are known to trigger immune thrombocytopenic purpura (ITP), but the disease is rarely described in association with coronavirus. We describe the case of acute ITP associated with coronavirus disease 19 (COVID-19) in an 86-year-old woman. Intravenous gamma-globulin and corticosteroids were effective on platelet count evolution.

摘要

血液学变化在冠状病毒感染中很常见,包括淋巴细胞减少和血小板减少。2002 - 2003年严重急性呼吸综合征冠状病毒(SARS-CoV)感染期间血小板减少很常见。血小板缺乏所涉及的机制尚不清楚。已知许多病毒会引发免疫性血小板减少性紫癜(ITP),但很少有该疾病与冠状病毒相关的描述。我们描述了一名86岁女性与新型冠状病毒肺炎(COVID-19)相关的急性ITP病例。静脉注射丙种球蛋白和皮质类固醇对血小板计数变化有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e926/8383652/b50b2faf40b5/jmc-11-166-g001.jpg

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