Wuhan Mental Health Center, Wuhan, China.
Shanghai Pudong New Area Mental Health Center, Tongji University School of Medicine, Shanghai, China.
J Psychosom Res. 2021 Jul;146:110509. doi: 10.1016/j.jpsychores.2021.110509. Epub 2021 May 10.
Somatoform disorders are frequently accompanied by panic attack and causes many clinical symptoms. This study aimed to compare clinical features between patients with and without panic attack in somatoform disorder.
In this cross-sectional study, 341 patients with somatoform disorder according to the MINI-International Neuropsychiatric Interview (M.I.N·I.) were divided into two groups depending on with or without comorbidity of a panic attack, somatoform disorder with a panic attack (SPA, n = 88) and those without panic attack (SNPA, n = 253). Patient Health Questionnaire (PHQ-15), Patient Health Questionnaire (PHQ-9) and 7-item Generalized Anxiety Disorder (GAD-7) scale was used to identify correlations between SPA group and SNPA group, respectively. Correlation analysis and multivariate regression analysis were used to determine the effects of demographic factors and psychiatric diagnoses on somatic, depressive and anxiety symptoms separately.
The SPA group's PHQ-15, PHQ-9 and GAD-7 scores were significantly higher than those of the SNPA group. Multiple linear regression analyses revealed that the associated factors for PHQ-15 were gender and panic disorder. PHQ-9 was just significantly associated with panic disorder. GAD-7 was significantly associated with education degree and panic disorder.
Our results suggest that somatoform disorder patients with panic attack suffered more severe clinical symptoms than those without a panic attack.
躯体形式障碍常伴有惊恐发作,并引起许多临床症状。本研究旨在比较躯体形式障碍患者伴发与不伴发惊恐发作的临床特征。
在这项横断面研究中,根据 MINI-国际神经精神访谈 (MINI) 将 341 名躯体形式障碍患者分为两组:伴惊恐发作的躯体形式障碍(SPA,n=88)和不伴惊恐发作的躯体形式障碍(SNPA,n=253)。使用患者健康问卷(PHQ-15)、患者健康问卷(PHQ-9)和 7 项广泛性焦虑障碍(GAD-7)量表分别识别 SPA 组和 SNPA 组之间的相关性。采用相关分析和多元回归分析,分别确定人口统计学因素和精神诊断对躯体、抑郁和焦虑症状的影响。
SPA 组的 PHQ-15、PHQ-9 和 GAD-7 评分显著高于 SNPA 组。多元线性回归分析显示,PHQ-15 的相关因素为性别和惊恐障碍。PHQ-9 仅与惊恐障碍显著相关。GAD-7 与受教育程度和惊恐障碍显著相关。
我们的结果表明,伴有惊恐发作的躯体形式障碍患者比不伴惊恐发作的患者有更严重的临床症状。