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轴位 MRI 检查中胫骨被动前脱位对膝关节前内侧进展性骨关节炎患者前交叉韧带功能缺失的诊断价值:一项病例对照研究。

Value of passive anterior tibial subluxation on axial MRI in identifying anterior cruciate ligament functional deficiency in patients with advanced anteromedial osteoarthritis of the knee: a case-control study.

机构信息

Department of Orthopaedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.

Department of Clinical Nutrition, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.

出版信息

BMC Musculoskelet Disord. 2021 May 13;22(1):434. doi: 10.1186/s12891-021-04328-z.

Abstract

BACKGROUND

A functionally deficient anterior cruciate ligament (ACL) is considered one of the contraindications in unicompartmental knee arthroplasty (UKA). But there is still a lack of standardized and reproducible methods to assess ACL functional integrity in patients with advanced anteromedial osteoarthritis of the knee (AMOA). This study explores the value of passive anterior tibial subluxation (PATS) on axial MRI in evaluating ACL status in this population.

METHODS

Patients who met UKA indications between November 2017 and September 2020 were included and grouped into "intact" (ACLI) or "deficient" (ACLD) group according to their ACL status during surgery. All participants underwent MRI with a standardized protocol. The measurements of medial and lateral PATS were conducted on axial MRI, and the mean of them was calculated as global PATS. Then the reliability and diagnostic ability of PATS were determined.

RESULTS

A total of 85 patients (45 for ACLI group, 40 for ACLD group) were included after selection. The measurements of PATS showed excellent intra- and inter-observer reliabilities (with an intraclass correlation coefficient of at least 0.986). The global PATS of the ACLI group was significantly lower than that of the ACLD group (- 2.30 ± 1.96 vs. 1.03 ± 1.96 mm, P<0.0001). The diagnostic ability of global PATS was good (area under the curve = 0.897), and a threshold of 1.2 mm had a specificity of 100%, a sensitivity of 55%, and an accuracy of 78.82%.

CONCLUSION

An axial global PATS of 1.2 mm on MRI is greatly specific for identifying a functionally deficient ACL in patients with advanced AMOA.

摘要

背景

功能不全的前交叉韧带(ACL)被认为是单髁膝关节置换术(UKA)的禁忌证之一。但是,目前仍然缺乏评估膝关节前内侧骨关节炎(AMOA)患者 ACL 功能完整性的标准化和可重复的方法。本研究旨在探讨轴向 MRI 上的被动胫骨前移(PATS)在评估该人群 ACL 状态中的价值。

方法

纳入 2017 年 11 月至 2020 年 9 月符合 UKA 适应证的患者,并根据术中 ACL 状态将其分为“完整”(ACLI)或“缺损”(ACLD)组。所有参与者均接受了标准化方案的 MRI 检查。在轴位 MRI 上测量内侧和外侧 PATS,并计算其平均值作为总体 PATS。然后确定 PATS 的可靠性和诊断能力。

结果

经筛选后,共纳入 85 例患者(ACLI 组 45 例,ACLD 组 40 例)。PATS 的测量值具有极好的观察者内和观察者间可靠性(至少 ICC 为 0.986)。ACLI 组的总体 PATS 明显低于 ACLD 组(-2.30±1.96 与 1.03±1.96 毫米,P<0.0001)。总体 PATS 的诊断能力良好(曲线下面积=0.897),阈值为 1.2 毫米时,特异性为 100%,敏感性为 55%,准确性为 78.82%。

结论

在患有晚期 AMOA 的患者中,MRI 上的轴向总体 PATS 为 1.2 毫米对识别功能不全的 ACL 具有高度特异性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d50c/8120852/8548ca060289/12891_2021_4328_Fig1_HTML.jpg

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