Obstetrics and Gynaecology, Queen Elizabeth Hospital, London, London, UK
Obstetrics and Gynaecology, Queen Elizabeth Hospital, London, London, UK.
BMJ Case Rep. 2021 May 13;14(5):e242094. doi: 10.1136/bcr-2021-242094.
A 52-year-old long-term user of the levonorgestrel-releasing intrauterine system (LNG-IUS) presented with vaginal bleeding. Endometrial biopsy was performed and revealed endometrioid adenocarcinoma. The patient had a laparoscopic hysterectomy and bilateral salpingo-oophorectomy. Endometrial cancer is rare in women with LNG-IUS as only seven cases have been published in the literature. Although scientific evidence shows LNG-IUS has a protective effect on the endometrium from developing cancer, our report highlights the importance of clinicians to be vigilant in cases of women with LNG-IUS who develop intermittent vaginal bleeding.
一位 52 岁的左炔诺孕酮宫内节育系统（LNG-IUS）长期使用者出现阴道出血。进行了子宫内膜活检，结果显示为子宫内膜样腺癌。患者接受了腹腔镜子宫切除术和双侧输卵管卵巢切除术。LNG-IUS 使用者中子宫内膜癌很少见，文献中仅报道了 7 例。尽管科学证据表明 LNG-IUS 对子宫内膜有保护作用，使其不易发生癌症，但我们的报告强调了临床医生在 LNG-IUS 使用者出现间歇性阴道出血时保持警惕的重要性。
