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新型冠状病毒肺炎:炎性关节炎的一个新元凶

COVID-19: An Emerging Culprit of Inflammatory Arthritis.

作者信息

Mukarram Muhammad Shariq, Ishaq Ghauri Muhammad, Sethar Sehrish, Afsar Nasir, Riaz Amir, Ishaq Khizra

机构信息

Department of Internal Medicine, Jinnah Medical College Hospital, Street 6, Sector 7-A, Korangi Industrial Area, Karachi, Pakistan.

Department of Medicine, Liaqat National Hospital, Karachi, Pakistan.

出版信息

Case Rep Rheumatol. 2021 Apr 26;2021:6610340. doi: 10.1155/2021/6610340. eCollection 2021.

Abstract

Arthralgia is one of the most common symptoms that occur in patients with COVID-19. About 15% of patients present with arthralgia at some point. Although COVID-19 seems to attack the musculoskeletal system (muscles and joints) in its infective and postinfective stage causing inflammatory arthritis, not much is known about the rheumatic manifestations of this infection. In this case series of 5 patients, we discuss the occurrence of bilaterally symmetrical polyarthritis in patients, previously free from any rheumatic disease, after encountering COVID-19 infection. The musculoskeletal manifestations in these patients phenotypically resembled rheumatoid arthritis. These patients were treated successfully with low-dose glucocorticoids and disease-modifying antirheumatic drugs (DMARDs).

摘要

关节痛是新冠病毒感染患者最常见的症状之一。约15%的患者在病程中的某个阶段会出现关节痛。尽管新冠病毒感染似乎在感染期和感染后期侵袭肌肉骨骼系统(肌肉和关节),引发炎症性关节炎,但对于这种感染的风湿性表现却知之甚少。在这个包含5例患者的病例系列中,我们讨论了既往无任何风湿性疾病的患者在感染新冠病毒后出现双侧对称性多关节炎的情况。这些患者的肌肉骨骼表现从表型上看类似于类风湿关节炎。这些患者通过低剂量糖皮质激素和改善病情抗风湿药(DMARDs)治疗成功。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f7/8077721/a98251ac4141/CRIRH2021-6610340.001.jpg

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