University of Groningen, University Medical Center Groningen, Department of Neurology, Groningen, The Netherlands.
Tremor Other Hyperkinet Mov (N Y). 2021 Apr 21;11:13. doi: 10.5334/tohm.603.
Long-term tremor recording is particularly useful for the assessment of overall severity and therapeutic interventions in tremor patients. The purpose of this paper is to investigate the optimal number of days needed to obtain reliable estimates of tremor percentage, tremor frequency variability and tremor intensity in tremor patients using long-term tremor recordings.
Participants were 18 years or older and were diagnosed with tremor by a movement disorders specialist. Participants wore an accelerometer on the wrist of the most affected arm during 30 consecutive days. Tremor presence, frequency variability and intensity were calculated per day. We used reliability analysis to determine the minimum number of days needed to obtain reliable estimates of these tremor characteristics.
Data from 36 adult organic (OrgT) and functional tremor (FT) patients (24 males; mean age 63.9 ± 11.9 years; 15 FT) were analyzed. Using five hours per day, one day of measurement is enough, except for tremor frequency variability in the OrgT group, where three days are needed and for tremor intensity where two days are always needed.
Visual analysis suggested that reliability can be increased considerably by using data from three days instead of one day even when using six hours of data per day. Three days with at least three hours of tremor data provide estimates of tremor percentage, frequency variability and intensity with good to excellent reliability, both for organic and functional tremor.
长期震颤记录对于评估震颤患者的整体严重程度和治疗干预特别有用。本文旨在研究使用长期震颤记录获得震颤患者震颤百分比、震颤频率变异性和震颤强度可靠估计所需的最佳天数。
参与者年龄在 18 岁或以上，由运动障碍专家诊断为震颤。参与者在最受影响的手臂的手腕上佩戴加速度计，持续 30 天。每天计算震颤的存在、频率变异性和强度。我们使用可靠性分析来确定获得这些震颤特征可靠估计所需的最小天数。
分析了 36 名成年器质性震颤（OrgT）和功能性震颤（FT）患者（24 名男性；平均年龄 63.9 ± 11.9 岁；15 名 FT）的数据。每天使用五小时，一天的测量就足够了，除了 OrgT 组的震颤频率变异性需要三天，而震颤强度总是需要两天。
即使每天使用六小时的数据，视觉分析表明，使用三天的数据而不是一天的数据可以大大提高可靠性。三天至少有三个小时的震颤数据可提供可靠的震颤百分比、频率变异性和强度估计，无论是器质性震颤还是功能性震颤，都具有良好到极好的可靠性。
