Cunnane S C
Efamol Research Institute, Kentville, Nova Scotia, Canada.
Lipids. 1988 Apr;23(4):372-4. doi: 10.1007/BF02537353.
Rats starved for 96 hr were shown to have a 94% reduction in liver triacylglycerol. Among the long chain fatty acids in liver triacylglycerol, only stearic acid and arachidonic acid were proportionally increased (2.5 and 6 times, respectively); palmitic and linoleic acids were unchanged, and palmitoleic and oleic acids were proportionally decreased. Stearic and arachidonic acids (mg%) were correlated positively within the triacylglycerol fraction, and both fatty acids varied inversely with total triacylglycerol (mg/g) in fed and starved rats. The utilization of long chain fatty acids from liver triacylglycerol during starvation resulted in selective retention of arachidonic acid and stearic acid and suggests that differential hydrolysis of liver triacylglycerol by hepatic lipase may occur or selective reacylation of these specific fatty acids may occur during starvation.
研究表明，饥饿96小时的大鼠肝脏三酰甘油减少了94%。在肝脏三酰甘油中的长链脂肪酸中，只有硬脂酸和花生四烯酸成比例增加（分别增加了2.5倍和6倍）；棕榈酸和亚油酸未发生变化，而棕榈油酸和油酸成比例减少。在三酰甘油组分中，硬脂酸和花生四烯酸（毫克%）呈正相关，并且在喂食和饥饿的大鼠中，这两种脂肪酸均与总三酰甘油（毫克/克）呈负相关。饥饿期间肝脏三酰甘油中长链脂肪酸的利用导致花生四烯酸和硬脂酸的选择性保留，这表明饥饿期间可能发生肝脏脂肪酶对肝脏三酰甘油的差异性水解，或者这些特定脂肪酸可能发生选择性再酰化。
