Zhao Yishen, Zhang Daqi, Zhou Le, Li Shijie, Wang Tie, Li Fang, Han Yujia, Dionigi Gianlorenzo, Sun Hui
Division of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, Changchun, China.
Division for Endocrine and Minimally Invasive Surgery, Department of Human Pathology in Adulthood and Childhood "Gaetano Barresi", University Hospital G. Martino, University of Messina, Messina, Italy.
Ann Transl Med. 2021 Apr;9(8):690. doi: 10.21037/atm-21-1229.
To investigate the optimal placement and size of adhesive thyroid cartilage electrodes (ATCEs) placed on the thyroid cartilage in porcine models for evaluating recurrent laryngeal nerve function compared with the other 3 recording electrode types.
Four Meishan piglets were used for this study. The electromyogram (EMG) signal stability was detected by intraoperative nerve monitoring (IONM). Best location and size of ATCEs were detected, and the EMG signals from each were compared. Latency data were tested by stimulating the different nerve points, and 6 manipulations of the trachea and endotracheal tube (ET) were applied to test the stability of EMG signals. ET electrodes, needle electrodes, and transcutaneous recording electrodes were simultaneously tested with comparison to ATCEs.
The optimal placement locations and sizes of ATCEs were determined. The amplitudes and latencies recorded from the ATCEs were consistent with those of the ET electrodes. More anti-interference was observed with the ATCEs than with the ET electrodes in surgical manipulations. ATCEs could be used during intermittent and continuous monitoring in similar fashion to ET electrodes and needle electrodes.
ATCEs had consistent monitoring function with ET electrodes and needle electrodes. Feasibility, EMG stability, and optimal location and size of ATCEs for IONM were resolved. The EMG profiles from the ATCEs were more stable during surgical manipulations.
在猪模型中，研究置于甲状软骨上的粘性甲状软骨电极（ATCEs）相对于其他3种记录电极类型，用于评估喉返神经功能时的最佳放置位置和尺寸。
本研究使用4只梅山仔猪。通过术中神经监测（IONM）检测肌电图（EMG）信号稳定性。检测ATCEs的最佳位置和尺寸，并比较各自的EMG信号。通过刺激不同神经点测试潜伏期数据，并进行6次气管和气管内导管（ET）操作以测试EMG信号的稳定性。同时将ET电极、针电极和经皮记录电极与ATCEs进行比较测试。
确定了ATCEs的最佳放置位置和尺寸。ATCEs记录的振幅和潜伏期与ET电极一致。在手术操作中，观察到ATCEs比ET电极具有更强的抗干扰能力。ATCEs可用于间歇性和连续性监测，方式与ET电极和针电极类似。
ATCEs与ET电极和针电极具有一致的监测功能。解决了ATCEs用于IONM的可行性、EMG稳定性以及最佳位置和尺寸问题。在手术操作期间，ATCEs的EMG图谱更稳定。
