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[利用放射性胶体研究网状内皮系统的功能]

[The function of the reticuloendothelial system studied with the use of radioactive colloids].

作者信息

Parfenov A S, Bondareva I B, Rudakov A V

出版信息

Med Radiol (Mosk). 1988 Jul;33(7):14-8.

PMID:3398749
Abstract

A new method for the interpretation of data obtained during radionuclide investigation of the reticuloendothelial system (RES) was proposed. It was based on a detailed description of the mechanism of reticuloendothelial extraction of a colloid injected intravenously. A model developed for this purpose included the main stages of radioactive colloid transport. The paper also represented a comparative analysis of the results of clinical examination of the controls and patients with liver cirrhosis. A 4-fold decrease of the blood flow in portal liver cirrhosis was noted as compared with normal mean indices in a 2-fold decrease in the specific blood supply of cells of the RES and in a 2-fold decrease in its volume. An increase in phagocytosis rate in patients with liver cirrhosis needs further verification.

摘要

提出了一种用于解释网状内皮系统(RES)放射性核素检查期间获得的数据的新方法。它基于对静脉注射胶体的网状内皮摄取机制的详细描述。为此开发的模型包括放射性胶体运输的主要阶段。本文还对对照组和肝硬化患者的临床检查结果进行了比较分析。与正常平均指标相比,门静脉肝硬化患者的血流量减少了4倍,RES细胞的特定血液供应减少了2倍,其体积减少了2倍。肝硬化患者吞噬率的增加需要进一步验证。

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