电离辐射对家犬的影响：原子弹试验时代的回顾。
The effects of ionizing radiation on domestic dogs: a review of the atomic bomb testing era.
机构信息
Department of Biological Sciences, University of South Carolina, Columbia, SC, 29208, U.S.A.
Graduate Partnerships Program, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, U.S.A.
出版信息
Biol Rev Camb Philos Soc. 2021 Oct;96(5):1799-1815. doi: 10.1111/brv.12723. Epub 2021 May 13.
Dogs were frequently employed as laboratory subjects during the era of atomic bomb testing (1950-1980), particularly in studies used to generate predictive data regarding the expected effects of accidental human occupational exposure to radiation. The bulk of these studies were only partly reported in the primary literature, despite providing vital information regarding the effects of radiation exposure on a model mammalian species. Herein we review this literature and summarize the biological effects in relation to the isotopes used and the method of radionuclide exposure. Overall, these studies demonstrate the wide range of developmental and physiological effects of exposure to radiation and radionuclides in a mid-sized mammal.
在原子弹试验时期（1950-1980 年），狗经常被用作实验室动物，特别是在用于生成有关意外人类职业辐射暴露预期影响的预测数据的研究中。尽管这些研究提供了有关辐射暴露对模型哺乳动物物种影响的重要信息，但大部分研究仅在主要文献中部分报道。在此，我们回顾了这一文献，并总结了与所用同位素和放射性核素暴露方法有关的生物学效应。总的来说，这些研究表明，在中型哺乳动物中，辐射和放射性核素暴露会产生广泛的发育和生理影响。
Zotero 插件