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既往产科病史并不影响短期中段尿道吊带术的结果。

Previous obstetrical history does not impact short-term mid-urethral sling outcomes.

机构信息

Division of Obstetrics and Gynaecology, Oslo University Hospital, Ullevål, PB 4950, Nydalen, 0424, Oslo, Norway.

Faculty of Medicine, University of Oslo, Oslo, Norway.

出版信息

Int Urogynecol J. 2021 Jul;32(7):1733-1743. doi: 10.1007/s00192-021-04836-5. Epub 2021 May 14.

DOI:10.1007/s00192-021-04836-5
PMID:33988787
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8295164/
Abstract

INTRODUCTION AND HYPOTHESIS

Pregnancy and delivery are known risk factors for stress and mixed urinary incontinence. The most common surgical treatment is mid-urethral sling (MUS) surgery. This study evaluated the potential impact of the obstetrical history on the short-term subjective and objective failure rates after MUS surgery.

METHODS

A registry-based surgical cohort study using data from the Medical Birth Registry of Norway (MBRN) and the national Norwegian Female Incontinence Registry (NFIR). Data from 14,787 women that underwent MUS surgery from 1998 to 2016 with complete registrations in the MBRN were included. Outcomes were 6-12-month postoperative subjective and objective failure rates. The potential impact of obstetrical and constitutional factors on both outcomes was tested in a multivariate logistic regression model.

RESULTS

Several obstetrical variables seemed to impact both outcomes in the univariate analyses. However, in the multivariate analyses, none of the obstetrical variables significantly impacted subjective failure, and only being nulliparous before MUS surgery remained a risk factor for objective failure [aOR 1.60, (95% CI 1.07-2.40), p = 0.022]. High body mass index at time of surgery, non-retropubic slings, high preoperative urgency symptom load, and surgical complications were all strong risk factors for poor outcomes in the multivariate analyses.

CONCLUSION

Although childbirth is considered a risk factor for developing stress urinary incontinence, childbirth does not appear to affect the result of MUS in parous women. Our results suggest that nulliparous women with SUI may have a different pathophysiology than SUI after childbirth.

摘要

引言和假设

妊娠和分娩是压力性和混合性尿失禁已知的风险因素。最常见的手术治疗方法是尿道中段吊带(MUS)手术。本研究评估了产科史对 MUS 手术后短期主观和客观失败率的潜在影响。

方法

这是一项基于注册的手术队列研究,使用来自挪威医学出生登记处(MBRN)和全国挪威女性尿失禁登记处(NFIR)的数据。纳入了 1998 年至 2016 年间接受 MUS 手术且 MBRN 完整登记的 14787 名女性的数据。结果为术后 6-12 个月的主观和客观失败率。在多变量逻辑回归模型中测试了产科和体质因素对这两个结果的潜在影响。

结果

在单变量分析中,几个产科变量似乎对两个结果都有影响。然而,在多变量分析中,产科变量均不显著影响主观失败,仅 MUS 手术前未生育是客观失败的危险因素[aOR 1.60,(95%CI 1.07-2.40),p=0.022]。手术时高体重指数、非经耻骨后吊带、术前急迫症状负荷高和手术并发症均是多变量分析中不良结局的强烈危险因素。

结论

尽管分娩被认为是压力性尿失禁的危险因素,但分娩似乎不会影响经产妇 MUS 的结果。我们的结果表明,初产妇的 SUI 可能与产后 SUI 的病理生理学不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f6a/8295164/5cb2e64bf28b/192_2021_4836_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f6a/8295164/5cb2e64bf28b/192_2021_4836_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f6a/8295164/5cb2e64bf28b/192_2021_4836_Fig1_HTML.jpg

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本文引用的文献

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Acta Obstet Gynecol Scand. 2020 Dec;99(12):1618-1625. doi: 10.1111/aogs.13951. Epub 2020 Jul 20.
2
The effect of childbirth on urinary incontinence: a matched cohort study in women aged 40-64 years.分娩对尿失禁的影响:40-64 岁女性的匹配队列研究。
Am J Obstet Gynecol. 2019 Oct;221(4):322.e1-322.e17. doi: 10.1016/j.ajog.2019.05.022. Epub 2019 May 21.
3
The effect of body mass index on retropubic midurethral slings.
体重指数对耻骨后尿道中段吊带的影响。
Am J Obstet Gynecol. 2019 Apr;220(4):371.e1-371.e9. doi: 10.1016/j.ajog.2018.12.018. Epub 2018 Dec 18.
4
Demographic risk factors for mid-urethral sling failure. Do they really matter?中尿道吊带失败的人口统计学风险因素。它们真的重要吗?
PLoS One. 2018 Nov 12;13(11):e0207185. doi: 10.1371/journal.pone.0207185. eCollection 2018.
5
Mid-urethral slings in young, middle-aged, and older women.年轻、中年和老年女性的中尿道吊带术。
Neurourol Urodyn. 2018 Nov;37(8):2578-2585. doi: 10.1002/nau.23583. Epub 2018 Sep 3.
6
Influence of age, BMI and parity on the success rate of midurethral slings for stress urinary incontinence.年龄、BMI 和产次对中尿道吊带治疗压力性尿失禁成功率的影响。
PLoS One. 2018 Aug 16;13(8):e0201167. doi: 10.1371/journal.pone.0201167. eCollection 2018.
7
Obesity and Stress Urinary Incontinence: Impact on Pathophysiology and Treatment.肥胖与压力性尿失禁:对病理生理学及治疗的影响
Curr Urol Rep. 2018 Feb 22;19(1):10. doi: 10.1007/s11934-018-0762-7.
8
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