Division of Thoracic Surgery, IRCCS Humanitas Research Hospital, Milan, Italy.
Department of Pathology, Humanitas Clinical and Research Center - IRCCS, Rozzano, Italy.
Thorac Cancer. 2021 Jul;12(13):2035-2038. doi: 10.1111/1759-7714.13992. Epub 2021 May 14.
Small cell lung cancer (SCLC) is an aggressive malignancy with a poor prognosis that accounts for 10% of all cases of clinical lung cancer. Due to its high growth fraction and rapid doubling time it is usually diagnosed as extensive local or metastatic disease in 60%-70% of cases. Combined small cell lung cancer (C-SCLC) is a relatively rare subtype of SCLC and is defined as SCLC combined with any elements of non-small cell lung cancer (NSCLC). Clinical presentation of SCLC as an isolated pedunculated endotracheal lesion is an especially rare occurrence. Here, we report for the first time the occurrence of a C-SCLC as a polypoid tumor of the trachea diagnosed in an 80-year-old woman admitted to the emergency department with a principal complaint of cough and wheezing.
小细胞肺癌（SCLC）是一种侵袭性恶性肿瘤，预后不良，占所有临床肺癌病例的 10%。由于其高生长分数和快速倍增时间，60%-70%的病例通常被诊断为广泛局部或转移性疾病。复合小细胞肺癌（C-SCLC）是 SCLC 一种相对罕见的亚型，定义为 SCLC 合并任何非小细胞肺癌（NSCLC）成分。作为孤立性带蒂气管内病变的 SCLC 的临床表现是一种特别罕见的情况。在这里，我们首次报告了一例 80 岁女性患者因咳嗽和喘息为主诉被收入急诊科，诊断为气管息肉样肿瘤的 C-SCLC。
