Department of Urology, Cancer Hospital of Guangxi Medical University and Guangxi Cancer Research Institute, Nanning, China.
Department of Radiology, Cancer Hospital of Guangxi Medical University and Guangxi Cancer Research Institute, Nanning, China.
J Int Med Res. 2021 May;49(5):3000605211014090. doi: 10.1177/03000605211014090.
Breast cancer metastasis to the ureter is rare. Fluorine-18-fluorodeoxyglucose positron emission tomography (18F-FDG PET)/computed tomography (CT) is widely used to identify primary lesions of metastatic tumours, however, 18F-FDG PET/CT imaging features of ureteral metastasis from breast cancer are rarely reported. Herein, the case of a 46-year-old woman with recurrent left flank pain for 5 months, who was admitted to the Cancer Hospital of Guangxi Medical University and Guangxi Cancer Research Institute, is described. She had undergone right radical mastectomy 5 years previously and had received tamoxifen treatment for 5 years. Assessment by 18F-FDG PET/CT revealed tumours on the ureter presenting as a long segmental lesion, radioactive concentrations, and a low maximum standardized uptake value (SUVmax), with no radioactive concentrations in the urine and no significant change in the ureteral contour. The severity of the ureteral lesion was not consistent with the severity of hydronephrosis. A tumour biopsy was performed laparoscopically, and postoperative pathological examination confirmed a primary breast cancer tumour. The patient did not consent to treatment and was lost to follow-up.
乳腺癌转移至输尿管较为罕见。氟-18-氟代脱氧葡萄糖正电子发射断层扫描(18F-FDG PET)/计算机断层扫描(CT)广泛用于识别转移性肿瘤的原发灶,然而,乳腺癌输尿管转移的 18F-FDG PET/CT 成像特征鲜有报道。本文报道了广西医科大学附属肿瘤医院暨广西壮族自治区肿瘤研究所收治的 1 例 46 岁女性患者,其因反复左侧腰痛 5 个月入院。该患者 5 年前曾接受右侧根治性乳房切除术,并接受了 5 年的他莫昔芬治疗。18F-FDG PET/CT 评估显示输尿管肿瘤呈长节段性病变,放射性浓聚,最大标准化摄取值(SUVmax)较低,尿液中无放射性浓度,输尿管轮廓无明显变化。输尿管病变的严重程度与肾积水的严重程度不一致。患者接受了腹腔镜下肿瘤活检,术后病理检查证实为原发性乳腺癌肿瘤。由于患者不同意治疗且失访,因此未进行进一步治疗。