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在公共精神卫生环境中,将创伤后应激障碍的辩证行为治疗延长暴露(DBT-PE)方案添加到 DBT 中是否会改善结果?一项具有基准测试的试点非随机有效性试验。

Does Adding the Dialectical Behavior Therapy Prolonged Exposure (DBT PE) Protocol for PTSD to DBT Improve Outcomes in Public Mental Health Settings? A Pilot Nonrandomized Effectiveness Trial With Benchmarking.

机构信息

University of Washington, Seattle; VA Puget Sound Health Care System.

University of Washington, Seattle; VA Puget Sound Health Care System.

出版信息

Behav Ther. 2021 May;52(3):639-655. doi: 10.1016/j.beth.2020.08.003. Epub 2020 Sep 1.

Abstract

The Dialectical Behavior Therapy Prolonged Exposure (DBT PE) protocol improves DBT's effects on PTSD in research settings, but its effectiveness in community settings is largely unknown. This pilot nonrandomized controlled trial examined DBT with and without DBT PE in four public mental health agencies. Patients (N = 35, 12-56 years old, 80.0% female, 64.7% racial/ethnic minorities, 44.1% sexual minorities) had PTSD, were receiving DBT, and completed assessments every four months over one year. Sixteen patients (45.7%) initiated DBT PE, 19 (54.3%) did not, and dropout did not differ between groups (31.3% vs. 26.3%). The primary barrier to initiating DBT PE was clinician turnover (57.9% of non-initiators). After adjusting for confounds, DBT PE initiators (g = 1.1) and completers (g = 1.4) showed a greater reduction in PTSD than patients who received DBT only (g = 0.5; p's < .05). Rates of reliable improvement in PTSD were 71.4% (DBT PE completers), 53.8% (DBT PE initiators), and 31.3% (DBT). Similar patterns were observed for posttraumatic cognitions, emotion dysregulation, general psychological distress, and limited activity days. There was no worsening of self-injurious behavior or crisis service use among patients who received DBT PE. Benchmarking analyses indicated comparable feasibility, acceptability, and safety, but a smaller magnitude of clinical change, than in efficacy studies. Results require replication in a randomized trial but suggest that DBT PE can be transported effectively to community settings.

摘要

辩证行为治疗延长暴露(DBT-PE)方案在研究环境中提高了 DBT 对 PTSD 的疗效,但在社区环境中的有效性尚不清楚。这项非随机对照试验研究了在四个公共心理健康机构中使用和不使用 DBT-PE 的 DBT。患者(N=35,12-56 岁,80.0%女性,64.7%为少数族裔,44.1%为性少数群体)患有 PTSD,正在接受 DBT,并在一年中每四个月完成一次评估。16 名患者(45.7%)开始接受 DBT-PE,19 名患者(54.3%)没有,两组的脱落率没有差异(31.3%对 26.3%)。启动 DBT-PE 的主要障碍是临床医生的更替(未启动者中有 57.9%)。在调整混杂因素后,启动 DBT-PE 的患者(g=1.1)和完成者(g=1.4)与仅接受 DBT 的患者(g=0.5;p<0.05)相比,PTSD 的减轻程度更大。PTSD 的可靠改善率分别为 71.4%(DBT-PE 完成者)、53.8%(DBT-PE 启动者)和 31.3%(DBT)。创伤后认知、情绪失调、一般心理困扰和活动受限天数也出现了类似的模式。接受 DBT-PE 的患者的自我伤害行为或危机服务使用没有恶化。基准分析表明,该方案具有相似的可行性、可接受性和安全性,但临床变化幅度较小,与疗效研究相当。结果需要在随机试验中复制,但表明 DBT-PE 可以有效地转移到社区环境中。

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