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骨髓纤维化患者颅内硬脑膜外髓外造血肿瘤酷似脑膜瘤:病例报告。

Intracranial sclerosing extramedullary haematopoietic tumour mimicking meningioma in a patient with myelofibrosis: Case report.

机构信息

Faculty of Medicine, University of Queensland, Herston, Queensland 4006, Australia.

Faculty of Medicine, University of Queensland, Herston, Queensland 4006, Australia; Pathology Queensland, Royal Brisbane and Women's Hospital, Herston, Queensland 4029, Australia.

出版信息

J Clin Neurosci. 2021 Jun;88:268-270. doi: 10.1016/j.jocn.2021.04.010. Epub 2021 Apr 24.

Abstract

Sclerosing extramedullary hematopoietic tumour is a rare tumour which can occur in certain myeloproliferative diseases, typically myelofibrosis. Typically these tumours present as a discrete retroperitoneal mass or masses, however they can occur in other sites within the body. In this case report we describe a 61-year old woman who underwent stealth guided bi-temporal craniotomy for resection of what was expected to be a large falx meningioma, however histopathology revealed the lesion to be a sclerosing extramedullary hematopoietic tumour. Following surgery, the patients post-operative recovery was complicated by intracerebral haemorrhage which required emergency evacuation and the patient remained in intensive care on a ventilator for 3 weeks. At one year follow up the patient reports her presenting symptoms of headaches, nausea, and vertigo had resolved.

摘要

骨外髓性硬化性造血肿瘤是一种罕见的肿瘤,可发生于某些骨髓增殖性疾病中,尤其是骨髓纤维化。这些肿瘤通常表现为腹膜后孤立性肿块,但也可发生于身体其他部位。在本病例报告中,我们描述了一位 61 岁女性患者,她接受了隐蔽引导下双侧颞部开颅术以切除预期为大型镰状脑膜瘤的病变,但组织病理学显示病变为骨外髓性硬化性造血肿瘤。手术后,患者的术后恢复因脑出血而复杂化,需要紧急清除血肿,患者在重症监护病房使用呼吸机 3 周。在 1 年的随访中,患者报告她的头痛、恶心和眩晕等症状已经缓解。

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