Division of Neurosurgery, Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Philippines.
Division of Neurosurgery, Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Philippines.
J Clin Neurosci. 2021 Jun;88:75-82. doi: 10.1016/j.jocn.2021.03.026. Epub 2021 Apr 1.
The coexistence of intracranial arteriovenous malformation (AVM) and meningioma in a single patient is seldom reported, so the clinical profile, optimal management, and outcomes of these patients are mostly unknown.
We performed a systematic review of the SCOPUS and PubMed databases for case reports and case series on patients with both intracranial AVMs and meningiomas. Data on demographics, clinical characteristics, surgical management, and outcomes were collected.
A total of 18 cases were reported in the literature, including the present case. The mean age at presentation was 54 years (range of 15-70 years), with no gender predilection. Most of the meningiomas and AVMs were frontal in location, and more than half of the lesions were contiguous. The most common presenting symptoms were seizures (67%), headache (44%), and weakness (33%). Majority of the patients underwent single stage meningioma and AVM excision (44%), followed by staged meningioma excision then AVM excision (17%) and meningioma excision only (17%). In all, 94% (17/18) of the meningiomas were excised compared to 72% (13/18) of the AVMs. Outcomes were reported in 15 patients; 80% were favorable, but there were 2 deaths and 1 tumor recurrence after 5 years.
The coexistence of an intracranial AVM with a meningioma is recognized but rarely reported in the literature. Individualized treatment should be employed in managing patients with concurrent lesions, and outcomes are generally favorable due to the benign nature of both these entities.
颅内动静脉畸形（AVM）和脑膜瘤同时存在于单一患者中较为少见，因此此类患者的临床特征、最佳治疗方法和预后大多未知。
我们对 SCOPUS 和 PubMed 数据库中的病例报告和病例系列进行了系统性回顾，以获取同时患有颅内 AVM 和脑膜瘤的患者的相关信息。收集了人口统计学、临床特征、手术管理和预后的数据。
文献中共报道了 18 例病例，包括本病例。发病时的平均年龄为 54 岁（15-70 岁），无性别差异。大多数脑膜瘤和 AVM 位于额叶，超过一半的病变是连续的。最常见的首发症状是癫痫（67%）、头痛（44%）和无力（33%）。大多数患者接受了脑膜瘤和 AVM 一期切除术（44%），其次是分期脑膜瘤切除术和 AVM 切除术（17%）以及单纯脑膜瘤切除术（17%）。总的来说，17/18（94%）例脑膜瘤被切除，而 13/18（72%）例 AVM 被切除。15 例患者报告了预后，80%的预后良好，但有 2 例死亡，5 年后有 1 例肿瘤复发。
颅内 AVM 合并脑膜瘤虽已被认识，但在文献中很少报道。对于同时存在病变的患者，应采用个体化治疗，由于这两种病变都是良性的，因此预后通常较好。
