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帕博利珠单抗治疗复发性呼吸道乳头瘤病稳定:病例报告。

Stabilization of Recurrent Respiratory Papillomatosis with Pembrolizumab Therapy: A Case Report.

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, San Francisco, CA.

Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, San Francisco, CA.

出版信息

J Voice. 2023 Jul;37(4):637.e1-637.e3. doi: 10.1016/j.jvoice.2021.03.017. Epub 2021 May 12.

DOI:10.1016/j.jvoice.2021.03.017
PMID:33992478
Abstract

Recurrent respiratory papillomatosis (RRP) is a benign neoplastic disease of the respiratory tract that is caused by human papilloma virus (HPV). The current standard of care is surgical excision with adjuvant treatment as needed. Multiple adjuvant treatments have been used with some success, but long-term control of disease remains difficult. We report on a case of a patient with a long history of RRP who had stabilized true vocal fold disease while on pembrolizumab for concurrent early stage lung squamous cell carcinoma.

摘要

复发性呼吸道乳头瘤病(RRP)是一种由人乳头瘤病毒(HPV)引起的呼吸道良性肿瘤性疾病。目前的标准治疗方法是手术切除,并根据需要进行辅助治疗。已经使用了多种辅助治疗方法,并取得了一定的成功,但疾病的长期控制仍然很困难。我们报告了一例长期患有 RRP 的患者,在接受 pembrolizumab 治疗同时期早期肺鳞状细胞癌期间,真声带疾病稳定。

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