呼吸频率增加对低强度运动时皮质氧合血红蛋白的影响。

Effects of increased respiratory rate on cortical oxygenated hemoglobin during low-intensity exercise.

机构信息

Department of Rehabilitation, Kobe City Medical Center General Hospital, Kobe, Japan.

Institute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, Japan.

出版信息

Respir Physiol Neurobiol. 2021 Sep;291:103691. doi: 10.1016/j.resp.2021.103691. Epub 2021 May 14.

DOI:10.1016/j.resp.2021.103691

PMID:33992799

Abstract

This study aimed to examine whether the end-tidal partial pressure of CO (PEtCO) affects the concentration of oxygenated hemoglobin (OHb) measured by near-infrared spectroscopy (NIRS). Participants were examined under the conditions of normal and increased ventilation. We measured OHb, mean blood pressure, skin blood flow, PEtCO, respiratory rate, and minute volume at 30 % of the maximum oxygen uptake during exercise. ΔOHb and PEtCO during exercise were lower in the increased ventilation than in the normal ventilation condition. Pearson's product-moment correlation analysis showed a significant positive correlation between ΔOHb and ΔMAP, ΔSBF, and PEtCO. Correlation coefficients were 0.249 (p < 0.001) for ΔMAP, 0.343 (p < 0.001) for ΔSBF, and 0.315 (p < 0.001) for PEtCO. In conclusion, we identified increased ventilation during bicycle ergometer exercise as a significant factor associated with significantly low PEtCO and ΔOHb.

摘要

本研究旨在探讨呼气末二氧化碳分压（PEtCO）是否会影响近红外光谱（NIRS）测量的氧合血红蛋白（OHb）浓度。参与者在正常通气和增加通气条件下进行检查。我们在运动中达到最大摄氧量的 30%时测量了 OHb、平均血压、皮肤血流、PEtCO、呼吸频率和分钟通气量。在增加通气条件下，运动时的ΔOHb 和 PEtCO 低于正常通气条件。Pearson 积矩相关分析显示，ΔOHb 与 ΔMAP、ΔSBF 和 PEtCO 之间存在显著正相关。相关系数分别为 0.249（p < 0.001）、0.343（p < 0.001）和 0.315（p < 0.001）。总之，我们发现自行车测力计运动期间增加通气是与 PEtCO 和 ΔOHb 显著降低相关的重要因素。