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静脉-静脉体外膜肺氧合辅助右主支气管袖式肺切除术。

Veno-venous extra-corporeal membrane oxygenation-assisted right tracheal-sleeve pneumonectomy.

机构信息

Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Milan, Italy.

Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.

出版信息

Interact Cardiovasc Thorac Surg. 2021 Oct 4;33(4):649-651. doi: 10.1093/icvts/ivab124.

DOI:10.1093/icvts/ivab124
PMID:33993258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8782225/
Abstract

Tracheal sleeve pneumonectomy for lung cancer is an old technique, and it is reserved for exceptional cases with tracheal carina involvement. Intra-operative airways management of this operation is incredibly complex, involving thoracic surgeons, anaesthesiologists and pulmonologists. We report a case of a 38-year-old male with no clinical history, referred to our department for an adenoid-cystic carcinoma involving distal trachea, carina and main right bronchus. Tracheal sleeve pneumonectomy was performed using extra-corporeal membrane oxygenation (ECMO). A veno-venous ECMO circuit was established through a heparin-coated percutaneous cannula in the right femoral vein and a heparin-coated percutaneous cannula in the internal right jugular vein by ultrasound assistance. No major complications occurred, and the patient was discharged after 30-day bronchoscopic control, showing the absence of fistula and negativity of the methylene blue test. ECMO-assisted surgery ensures adequate respiratory support, haemodynamic stability, lower risk of bleeding complications with a clean operating field and better brain and myocardial oxygenation.

摘要

气管袖状切除术治疗肺癌是一种古老的技术,仅保留用于气管隆突受累的特殊情况。该手术的术中气道管理极其复杂,涉及胸外科医生、麻醉师和肺科医生。我们报告了一例 38 岁男性病例,无临床病史,因累及远端气管、隆突和主右支气管的腺样囊性癌而被转诊至我科。使用体外膜氧合 (ECMO) 进行气管袖状切除术。通过超声辅助,在右股静脉和内颈静脉内置入肝素涂层经皮插管建立静脉-静脉 ECMO 回路。未发生重大并发症,患者在 30 天支气管镜检查控制后出院,显示无瘘管且亚甲蓝试验阴性。ECMO 辅助手术可确保充分的呼吸支持、血流动力学稳定、较低的出血并发症风险、清洁的手术视野以及更好的脑和心肌氧合。

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本文引用的文献

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Multivariate Analysis of Risk Factor for Mortality and Feasibility of Extracorporeal Membrane Oxygenation in High-Risk Thoracic Surgery.高危胸外科体外膜肺氧合治疗死亡风险因素的多因素分析及可行性评估。
Ann Thorac Cardiovasc Surg. 2021 Apr 20;27(2):97-104. doi: 10.5761/atcs.oa.20-00224. Epub 2021 Feb 3.
2
Preliminary Results of Extracorporeal Membrane Oxygenation Assisted Tracheal Sleeve Pneumonectomy for Cancer.体外膜肺氧合辅助气管袖状肺叶切除术治疗癌症的初步结果
Thorac Cardiovasc Surg. 2021 Apr;69(3):240-245. doi: 10.1055/s-0040-1714071. Epub 2020 Aug 19.
3
The pumpless extracorporeal lung membrane provides complete respiratory support during complex airway reconstructions without inducing cellular trauma or a coagulatory and inflammatory response.无泵体外肺膜在复杂气道重建过程中提供完全的呼吸支持,而不会引起细胞创伤或凝血和炎症反应。
J Thorac Cardiovasc Surg. 2012 Aug;144(2):425-30. doi: 10.1016/j.jtcvs.2012.04.002. Epub 2012 May 9.
4
Experiences with the surgical resection of the human carina, tracheal wall, and contralateral bronchial wall in cases of right total pneumonectomy.右全肺切除术中对人体隆突、气管壁及对侧支气管壁进行手术切除的经验。
J Thorac Surg. 1950 Jun;19(6):906-22.