Department of Cardiovascular Medicine, Kitajima Taoka Hospital, Tokushima, Japan.
Department of Cardiovascular Medicine, Tokushima University Hospital, Tokushima, Japan.
J Med Invest. 2021;68(1.2):189-191. doi: 10.2152/jmi.68.189.
The patient with congenital hypogonadotropic hypogonadism (HH) shows low serum levels of androgen, which is a group of sex hormones including testosterone, caused by the decreased gonadotropin release in the hypothalamus. Recent reports showed androgens exert protective effects against insulin resistance or atherosclerotic diseases, such as diabetes mellitus or coronary artery disease. However, whether the juvenile hypogonadism affects the diabetes or cardiovascular disease is unclear. We report a case of a middle-aged man with congenital HH who had severe coronary artery disease complicated with metabolic disorders. J. Med. Invest. 68 : 189-191, February, 2021.
患有先天性低促性腺激素性性腺功能减退症（HH）的患者表现为血清雄激素水平降低，雄激素是一组包括睾酮在内的性激素，由下丘脑促性腺激素释放减少引起。最近的报告显示，雄激素对胰岛素抵抗或动脉粥样硬化性疾病（如糖尿病或冠状动脉疾病）具有保护作用。然而，青春期性腺功能减退症是否会影响糖尿病或心血管疾病尚不清楚。我们报告了 1 例中年男性先天性 HH 患者，他患有严重的冠状动脉疾病并伴有代谢紊乱。J. Med. Invest. 68 : 189-191, February, 2021.
