意大利α-1抗胰蛋白酶缺乏症与COVID-19感染之间的地理重叠：偶然还是因果关系？ - Suppr

Geographical Overlap Between Alpha-1 Antitrypsin Deficiency and COVID-19 Infection in Italy: Casual or Causal?

作者信息

Vianello Andrea, Braccioni Fausto

机构信息

Respiratory Pathophysiology Division, Department of Cardio-Thoracic and Vascular Sciences, University of Padova, Padova, Italy.

出版信息

Arch Bronconeumol (Engl Ed). 2020 Sep;56(9):609-610. doi: 10.1016/j.arbr.2020.05.011. Epub 2020 Sep 14.

DOI:10.1016/j.arbr.2020.05.011

PMID:33994645

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7261431/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8fc/7261431/4d9ae41505a5/gr1_lrg.jpg

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Geographical Overlap Between Alpha-1 Antitrypsin Deficiency and COVID-19 Infection in Italy: Casual or Causal?

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Geographical Overlap Between Alpha-1 Antitrypsin Deficiency and COVID-19 Infection in Italy: Casual or Causal?

作者信息

Vianello Andrea, Braccioni Fausto

机构信息

Respiratory Pathophysiology Division, Department of Cardio-Thoracic and Vascular Sciences, University of Padova, Padova, Italy.

出版信息

Arch Bronconeumol (Engl Ed). 2020 Sep;56(9):609-610. doi: 10.1016/j.arbr.2020.05.011. Epub 2020 Sep 14.

DOI:10.1016/j.arbr.2020.05.011

PMID:33994645

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7261431/

Abstract

摘要

相似文献

Geographical Overlap Between Alpha-1 Antitrypsin Deficiency and COVID-19 Infection in Italy: Casual or Causal?

Arch Bronconeumol (Engl Ed). 2020 Sep;56(9):609-610. doi: 10.1016/j.arbr.2020.05.011. Epub 2020 Sep 14.

α1-Antitrypsin deficiency and the risk of COVID-19: an urgent call to action.

Lancet Respir Med. 2021 Apr;9(4):337-339. doi: 10.1016/S2213-2600(21)00018-7. Epub 2021 Jan 21.

COVID-19 infection in severe Alpha 1-antitrypsin deficiency: Looking for a rationale.

Respir Med. 2021 Jul;183:106440. doi: 10.1016/j.rmed.2021.106440. Epub 2021 Apr 30.

COVID-19 vaccination in patients with α1-antitrypsin deficiency.

Lancet Respir Med. 2021 Aug;9(8):818-820. doi: 10.1016/S2213-2600(21)00271-X. Epub 2021 Jun 18.

Alpha 1 Antitrypsin Therapy in Patients with Alpha 1 Antitrypsin Deficiency: Perspectives from a Registry Study and Practical Considerations for Self-Administration During the COVID-19 Pandemic.

Int J Chron Obstruct Pulmon Dis. 2021 Nov 1;16:2983-2996. doi: 10.2147/COPD.S325211. eCollection 2021.

Prevalence and phenotype of subjects carrying rare variants in the Italian registry for alpha1-antitrypsin deficiency.

J Med Genet. 2005 Mar;42(3):282-7. doi: 10.1136/jmg.2004.023903.

Alpha-1 antitrypsin deficiency severity and the risk of COVID-19: A Portuguese cohort.

Respir Med. 2021 May;181:106387. doi: 10.1016/j.rmed.2021.106387. Epub 2021 Apr 2.

Alpha-1 antitrypsin deficiency: from Italy to the world.

Monaldi Arch Chest Dis. 2007 Dec;67(4):176-8. doi: 10.4081/monaldi.2007.474.

Correlation of alpha-1 antitrypsin levels and exosome associated neutrophil elastase endothelial injury in subjects with SARS-CoV2 infection.

PLoS One. 2022 Sep 9;17(9):e0274427. doi: 10.1371/journal.pone.0274427. eCollection 2022.

Alpha-1 antitrypsin deficiency in Italy: regional differences of the PIS and PIZ deficiency alleles.

Monaldi Arch Chest Dis. 2005 Sep;63(3):133-41. doi: 10.4081/monaldi.2005.630.

引用本文的文献

Alpha-1 antitrypsin in COVID-19 patients: a dual-center screening study in Malaysia.

Ann Saudi Med. 2025 Jul-Aug;45(4):225-234. doi: 10.5144/0256-4947.2025.225. Epub 2025 Aug 7.

Advancing the understanding and treatment of lung pathologies associated with alpha 1 antitrypsin deficiency.

Ther Adv Respir Dis. 2025 Jan-Dec;19:17534666251318841. doi: 10.1177/17534666251318841.

COVID-19 in Individuals with Severe Alpha 1-Antitrypsin Deficiency.

Int J Chron Obstruct Pulmon Dis. 2024 Dec 9;19:2661-2669. doi: 10.2147/COPD.S482323. eCollection 2024.

The Inhibition of Serine Proteases by Serpins Is Augmented by Negatively Charged Heparin: A Concise Review of Some Clinically Relevant Interactions.

Int J Mol Sci. 2024 Feb 2;25(3):1804. doi: 10.3390/ijms25031804.

Evaluation of serum vitamin B12 levels in patients with COVID-19 infection: A case-control study.

J Med Biochem. 2023 Aug 25;42(3):524-529. doi: 10.5937/jomb0-42357.

Alpha-1-antitrypsin antagonizes COVID-19: a review of the epidemiology, molecular mechanisms, and clinical evidence.

Biochem Soc Trans. 2023 Jun 28;51(3):1361-1375. doi: 10.1042/BST20230078.

Comparison of COVID-19 Outcomes With Alpha-1 Antitrypsin Deficiency Prevalence in Europe: A Cross-Sectional Study.

Cureus. 2023 Jan 27;15(1):e34293. doi: 10.7759/cureus.34293. eCollection 2023 Jan.

Abnormal Alpha-1 Antitrypsin Levels and Other Risk Factors Associated with Lung Function Impairment at 6 and 12 Months after Hospitalization Due to COVID-19: A Cohort Study.

Healthcare (Basel). 2022 Nov 22;10(12):2341. doi: 10.3390/healthcare10122341.

Proteolysis and Deficiency of α1-Proteinase Inhibitor in SARS-CoV-2 Infection.

Biochem Mosc Suppl B Biomed Chem. 2022;16(4):271-291. doi: 10.1134/S1990750822040035. Epub 2022 Nov 16.

Impact of COVID-19 in Patients With Severe Alpha-1 Antitrypsin Deficiency: The IMCA1 Study of the EARCO Clinical Research Collaboration.

Arch Bronconeumol. 2022 Dec;58(12):840-842. doi: 10.1016/j.arbres.2022.07.002. Epub 2022 Jul 11.

本文引用的文献

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.

Cell. 2020 Apr 16;181(2):271-280.e8. doi: 10.1016/j.cell.2020.02.052. Epub 2020 Mar 5.

Genetic epidemiology of alpha-1 antitrypsin deficiency in southern Europe: France, Italy, Portugal and Spain.

Clin Genet. 2003 Jun;63(6):490-509. doi: 10.1034/j.1399-0004.2003.00078.x.

Geographical Overlap Between Alpha-1 Antitrypsin Deficiency and COVID-19 Infection in Italy: Casual or Causal?

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Geographical Overlap Between Alpha-1 Antitrypsin Deficiency and COVID-19 Infection in Italy: Casual or Causal?

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