Li Anning, Zhao Jiawei, Fu Jingru, Cai Jia, Zhang Peng
Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
Asian J Pharm Sci. 2021 Mar;16(2):161-174. doi: 10.1016/j.ajps.2019.08.001. Epub 2019 Sep 5.
The lack of effective methods of diagnosis and treatment presents a major barrier to combat against tumor. The biomimetic concept is an emerging field that expresses great application potential in tumor fighting. Strategy for combining nano-systems with biomimetic technology has gained increasing attention that is proved bioinspired, environmentally benign, and promising. Herein, we provide an up-to-date review of biomimetic nano-systems as well as their applications in tumor therapy. In addition, the challenges and future directions of biomimetic nano-systems to achieve clinical translation are also pointed out.
缺乏有效的诊断和治疗方法是对抗肿瘤的主要障碍。仿生概念是一个新兴领域,在肿瘤防治方面展现出巨大的应用潜力。将纳米系统与仿生技术相结合的策略已受到越来越多的关注,事实证明这种策略具有生物启发性、环境友好性且前景广阔。在此,我们对仿生纳米系统及其在肿瘤治疗中的应用进行了最新综述。此外,还指出了仿生纳米系统实现临床转化面临的挑战和未来方向。