Division of General Surgery, Department of Surgery, College of Medicine, King Faisal University, Riyadh, Kingdom of Saudi Arabia.
Pan Afr Med J. 2021 Feb 23;38:204. doi: 10.11604/pamj.2021.38.204.27503. eCollection 2021.
the aim of this retrospective study is to review patients with malignant goiter, as regards their nature, demographic characterization, clinical presentation and preoperative histopathological data.
the study focused on a period of 4 years from December 2015 to January 2019. Patients´ demographic data, clinical presentation, Intra-operative findings, Pre and postoperative histopathological staging and grading were all recorded. Postoperative follow up whether early or late were also included.
a total of 100% (n = 65) patients underwent surgery. The female to male ratio was found to be 5:1 (48 females and 17 males). Solitary nodule was the main clinical presentation in 80% (n = 52) of cases while 20% (n = 13) were multinodular swellings. Papillary carcinoma was recorded in 80% (n = 52) of patients while in 15.4% (n =10) of patients were having follicular carcinoma. The remaining 4.6% (n = 3) suffered of lymphoma; no medullary or anaplastic tumors were reported.
thyroid cancer is the most commonly encountered endocrinal malignancy at our institute. Fine Needle Aspiration Cytology (FNAC) showed a high percentage of reliability in diagnosing thyroid cancer among our series. It is recommended to adapt this technique in initial screening of goiter patients in our local setting.
本回顾性研究旨在分析甲状腺恶性肿瘤患者的发病特征、临床表现、术前病理组织学检查结果等。
研究时间为 2015 年 12 月至 2019 年 1 月，共 4 年。记录患者的一般资料、临床表现、术中所见、术前和术后病理分期及分级，包括术后随访（早期或晚期）。
共 65 例患者接受手术治疗，男女比例为 5:1（48 例女性，17 例男性）。80%（n=52）的患者以单发结节为主要临床表现，20%（n=13）为多结节性肿胀。80%（n=52）的患者为乳头状癌，15.4%（n=10）为滤泡状癌，4.6%（n=3）为淋巴瘤；未报告髓样癌或间变性癌。
甲状腺癌是本机构最常见的内分泌恶性肿瘤。细针穿刺细胞学检查（FNAC）在本研究系列中对甲状腺癌的诊断具有较高的可靠性。建议在本地区的甲状腺肿患者的初步筛查中采用该技术。
