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单纯型中央性牙源性纤维瘤:一项原始观察。

Central odontogenic fibroma of simple type: An original observation.

作者信息

Oueslati Yassine, Belkacem Chebil Raouaa, Oualha Lamia, Mziou Zouha, Moatemri Ramzi, Sriha Badreddine, Douki Nabiha

机构信息

Department of Oral Medicine and Oral Surgery, SAHLOUL Hospital (Sousse), Dental Faculty of Monastir, University of Monastir, Sousse, Tunisia.

Laboratory of Oral Health and Maxillofacial Rehabilitation (LR12ES11), University of Monastir, Sousse, Tunisia.

出版信息

SAGE Open Med Case Rep. 2021 Apr 28;9:2050313X211012494. doi: 10.1177/2050313X211012494. eCollection 2021.

DOI:10.1177/2050313X211012494
PMID:33996090
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8107670/
Abstract

Central odontogenic fibroma is an uncommon, benign, slow-growing intraosseous mesenchymal odontogenic tumour. It presents a diagnostic dilemma to the clinician and the pathologist because its clinical and radiological features resemble other odontogenic and/or non-odontogenic tumours, and the differential diagnosis is based on histological examination. In this report, we describe our experience with a case of a 23-year-old female patient with central odontogenic fibroma of the mandible that was diagnosed as 'simple type'. Highlighting a subtype that was dropped from the last World Health Organization classification of head and neck tumours is important to accumulate more information about this lesion and to show its different features. Despite its rarity, central odontogenic fibroma should be included in the differential diagnosis of intrabony tumours of the jaws. These findings can better educate oral and maxillofacial surgeons about the unusual nature of this lesion, help establish a correct diagnosis and give the appropriate therapeutic management.

摘要

中央性牙源性纤维瘤是一种罕见的、良性的、生长缓慢的骨内间叶性牙源性肿瘤。它给临床医生和病理学家带来了诊断难题,因为其临床和影像学特征与其他牙源性和/或非牙源性肿瘤相似,鉴别诊断基于组织学检查。在本报告中,我们描述了一例23岁女性下颌骨中央性牙源性纤维瘤患者的诊疗经验,该病例被诊断为“单纯型”。强调一种从世界卫生组织上一版头颈部肿瘤分类中删除的亚型,对于积累更多关于该病变的信息并展示其不同特征具有重要意义。尽管中央性牙源性纤维瘤很罕见,但在颌骨骨内肿瘤的鉴别诊断中应将其纳入考虑。这些发现可以更好地让口腔颌面外科医生了解该病变的特殊性,有助于建立正确的诊断并给予适当的治疗管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1dd/8107670/a7fb36e873e9/10.1177_2050313X211012494-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1dd/8107670/11840f358e63/10.1177_2050313X211012494-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1dd/8107670/ce5717d8a1c1/10.1177_2050313X211012494-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1dd/8107670/38936f9d42ef/10.1177_2050313X211012494-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1dd/8107670/0a396bfedd51/10.1177_2050313X211012494-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1dd/8107670/a7fb36e873e9/10.1177_2050313X211012494-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1dd/8107670/11840f358e63/10.1177_2050313X211012494-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1dd/8107670/ce5717d8a1c1/10.1177_2050313X211012494-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1dd/8107670/38936f9d42ef/10.1177_2050313X211012494-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1dd/8107670/0a396bfedd51/10.1177_2050313X211012494-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1dd/8107670/a7fb36e873e9/10.1177_2050313X211012494-fig5.jpg

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Imaging Sci Dent. 2019 Sep;49(3):229-234. doi: 10.5624/isd.2019.49.3.229. Epub 2019 Sep 24.
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Odontogenic Tumors: Imaging-Based Review of the Fourth Edition of World Health Organization Classification.牙源性肿瘤:基于影像学对世界卫生组织第四版分类的综述
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Central odontogenic fibroma: An updated systematic review of cases reported in the literature with emphasis on recurrence influencing factors.
中央性牙源性纤维瘤:文献报道病例的更新系统回顾,重点关注复发影响因素。
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Large mandibular central odontogenic fibroma documented over 20 years: A case report.20多年来记录的大型下颌中央牙源性纤维瘤:病例报告
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A curious case of central odontogenic fibroma: A novel perspective.一例罕见的中央性牙源性纤维瘤病例:一种新视角。
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Oncogenic signalling pathways in benign odontogenic cysts and tumours.良性牙源性囊肿和肿瘤中的致癌信号通路。
Oral Oncol. 2017 Sep;72:165-173. doi: 10.1016/j.oraloncology.2017.07.021. Epub 2017 Jul 27.
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