Diehl Kyra L, Cohen Philip R
Osteopathic Medicine, Western University of Health Sciences, Pomona, USA.
Dermatology, San Diego Family Dermatology, National City, USA.
Cureus. 2021 Apr 12;13(4):e14443. doi: 10.7759/cureus.14443.
The long-term use of topical corticosteroids can result in rosacea-like dermatitis or facial perioral dermatitis. The case of a 54-year-old man is described who developed topical corticosteroid-induced perioral dermatitis (TOP STRIPED), and the features of topical corticosteroid-induced rosacea-like dermatitis are reviewed. The man presented with a painful erythematous facial eruption. Additional history revealed that he had been applying a high-potency topical corticosteroid twice daily to the affected area. Correlation of the clinical history and cutaneous examination established a diagnosis of topical corticosteroid-induced rosacea-like dermatitis (TOP SIDE RED). Treatment of the patient's TOP SIDE RED included not only discontinuing the high-potency corticosteroid but also initiating topical and oral antibiotics. In addition, a low-potency topical corticosteroid and metronidazole gel were also applied to the affected area. His facial rash resolved within three months and has not recurred. TOP STRIPED, also referred to as TOP SIDE RED, is an adverse side effect associated with the use of high-potency topical corticosteroids to the face. Management includes discontinuing the corticosteroid. Additional treatment may include a low-potency topical corticosteroid, antibiotics (systemic or topical or both), and/or topical calcineurin inhibitors, such as tacrolimus or pimecrolimus.
长期使用外用糖皮质激素可导致酒渣鼻样皮炎或面部口周皮炎。本文描述了一名54岁男性发生外用糖皮质激素诱发口周皮炎(TOP STRIPED)的病例,并对外用糖皮质激素诱发酒渣鼻样皮炎的特征进行了综述。该男性表现为面部疼痛性红斑疹。进一步询问病史发现,他一直在受影响区域每日两次外用强效糖皮质激素。结合临床病史和皮肤检查确诊为外用糖皮质激素诱发酒渣鼻样皮炎(TOP SIDE RED)。该患者TOP SIDE RED的治疗不仅包括停用强效糖皮质激素,还包括开始外用和口服抗生素。此外,还在受影响区域外用了低效糖皮质激素和甲硝唑凝胶。他面部皮疹在三个月内消退且未复发。TOP STRIPED,也称为TOP SIDE RED,是与面部使用强效外用糖皮质激素相关的一种不良副作用。处理措施包括停用糖皮质激素。额外的治疗可能包括低效外用糖皮质激素、抗生素(全身或局部或两者联用)和/或外用钙调神经磷酸酶抑制剂,如他克莫司或吡美莫司。