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[荷瘤45大鼠脑部在放疗过程中的代谢变化以及热疗对肿瘤的影响]

[Brain metabolism of sarcoma 45-bearing rats undergoing radiation and the effect of hyperthermia on the tumor].

作者信息

Khripchenko I P, Pikulev A T, Kukulianskaia M F, Val'shteĭn M M, Burtseva O E

出版信息

Radiobiologiia. 1988 May-Jun;28(3):371-6.

PMID:3399638
Abstract

Activity of hexokinase and acetylcholinesterase and pyridoxal co-enzyme content of brain subcellular fractions were studied in rats, bearing sarcoma 45, after local exposure of the tumor to 20 Gy X-radiation and microwave hyperthermia. The carbohydrate metabolism was sharply inhibited while the pyridoxal coenzyme content and acetylcholinesterase activity increased.

摘要

对患有肉瘤45的大鼠,在肿瘤局部接受20 Gy X射线辐射和微波热疗后,研究了脑亚细胞组分中己糖激酶和乙酰胆碱酯酶的活性以及吡哆醛辅酶含量。碳水化合物代谢受到显著抑制,而吡哆醛辅酶含量和乙酰胆碱酯酶活性增加。

相似文献

1
[Brain metabolism of sarcoma 45-bearing rats undergoing radiation and the effect of hyperthermia on the tumor].[荷瘤45大鼠脑部在放疗过程中的代谢变化以及热疗对肿瘤的影响]
Radiobiologiia. 1988 May-Jun;28(3):371-6.
2
[The content of pyridoxal coenzymes in the brain and liver of rats exposed to a single irradiation with x-rays].[单次X射线照射后大鼠脑和肝脏中吡哆醛辅酶的含量]
Radiobiologiia. 1989 Jan-Feb;29(1):70-3.
3
[Aspartate aminotransferase and glutamate dehydrogenase activity in the rat brain during infrared laser exposure].[红外激光照射期间大鼠脑中的天冬氨酸转氨酶和谷氨酸脱氢酶活性]
Radiobiologiia. 1989 Mar-Apr;29(2):274-6.
4
[Pyridoxal coenzyme content in the tissues of irradiated animals as affected by adrenoblockaders in in vitro experiments].[体外实验中肾上腺阻滞剂对受辐照动物组织中吡哆醛辅酶含量的影响]
Radiobiologiia. 1981 Sep-Oct;21(5):772-6.
5
[Effect of local thermal and radiation effects on the enzymatic activity of tumor tissue hydrolases].[局部热效应和辐射效应对肿瘤组织水解酶活性的影响]
Biull Eksp Biol Med. 1984 Jul;98(7):39-41.
6
Effect of different levels of vitamin B6 in the diet of rats on the content of pyridoxamine-5'-phosphate and pyridoxal-5'-phosphate in the liver.大鼠饮食中不同水平维生素B6对肝脏中磷酸吡哆胺-5'-磷酸和磷酸吡哆醛-5'-磷酸含量的影响。
Int J Vitam Nutr Res. 1982;52(4):407-16.
7
[The characteristics of sarcoma M-1 in rats].
Nauchnye Doki Vyss Shkoly Biol Nauki. 1990(6):154-60.
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[Effect of local hyperthermia and irradiation on animal tumors].
Med Radiol (Mosk). 1981 May;26(5):32-6.
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[Subcellular localization, isoenzyme spectrum and properties of hexokinase from sarcoma M-1].
Vopr Med Khim. 1975 Nov-Dec;21(6):609-13.
10
[Pyridoxal phosphate as an agent for normalizing the monoamine oxidase activity of the brain in radiation sickness].[磷酸吡哆醛作为使放射病中大脑单胺氧化酶活性恢复正常的药物]
Med Radiol (Mosk). 1990 Jun;35(6):23-4.