Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.
Department of Cardiology, Suqian First People's Hospital, Suqian, Jiangsu 223800, China.
Biomed Res Int. 2021 Apr 27;2021:5551325. doi: 10.1155/2021/5551325. eCollection 2021.
The study was aimed at exploring the electrophysiological characteristics (EPS) of the optimal ablation site and its relationship with electroanatomic voltage mapping (EVM) in idiopathic premature ventricular contractions (PVCs) originating from the right ventricular outflow tract (RVOT).
A total of 28 patients with idiopathic RVOT PVCs underwent successful ablation and EVM using a 3D electroanatomical mapping (CARTO) system.
Both bipolar and unipolar EVM showed a similar band-like lower-voltage area (LVA) under the pulmonary valve in all the patients; 21.4% of the targets were located in the band-like LVA. 42.9% of the targets were at the border of the band-like LVA on the bipolar voltage map, but unipolar mapping showed that 53.6% of the targets were located in the band-like LVA, and 35.7% of the targets at the border of the band-like LVA. A significant difference was found in both unipolar and bipolar voltage values between the regions within 0-5 mm above the optimal ablation site and the other regions. A similar difference was observed only in unipolar voltage values below the optimal ablation site. At the ablation site, there were frequent occurrences of a fragmented wave and voltage reversion in the bipolar electrograms, frustrated falling limbs, W bottom, and a QS configuration width > 150 ms in the unipolar electrograms.
EVM showed that the band-like LVA was an interesting area for the search of the optimal ablation sites of idiopathic RVOT-PVCs, especially the border area. There was focal microscarring around the ablation targets; some characteristics of EPS proved significant for successful ablation.
本研究旨在探讨特发性右心室流出道(RVOT)室性期前收缩(PVC)最佳消融部位的电生理特征(EPS)及其与电解剖电压标测(EVM)的关系。
共 28 例特发性 RVOT PVC 患者成功接受了 3D 电解剖标测(CARTO)系统下的消融和 EVM。
所有患者的肺动脉瓣下均呈现类似的双极和单极低电压区(LVA)宽带;21.4%的靶点位于 LVA 带内。42.9%的靶点位于双极电压图 LVA 带的边缘,但单极标测显示 53.6%的靶点位于 LVA 带内,35.7%的靶点位于 LVA 带的边缘。在最佳消融部位上方 0-5mm 以内的区域与其他区域之间,单极和双极电压值存在显著差异。仅在最佳消融部位下方才能观察到单极电压值的类似差异。在消融部位,双极电图中经常出现碎裂波和电压反转、沮丧下降支、W 型底部和 QS 构型宽度>150ms;单极电图中也存在类似的电压反转。
EVM 显示,宽带 LVA 是寻找特发性 RVOT-PVC 最佳消融部位的有趣区域,尤其是边缘区域。消融靶点周围存在局灶性微瘢痕;EPS 的一些特征对成功消融具有重要意义。