磷酸雌莫司汀治疗雌激素抵抗性前列腺癌
The treatment of oestrogen-escaped carcinoma of the prostate with estramustine phosphate.
作者信息
Chisholm G D, O'Donoghue E P, Kennedy C L
出版信息
Br J Urol. 1977;49(7):717-20. doi: 10.1111/j.1464-410x.1977.tb04559.x.
Abstract
30 patients with oestrogen-escaped carcinoma of the prostate have been treated with estramustine phosphate (Estracyt). 27% showed a partial objective response and 33% had a subjective response. The terms used for defining a response are challenged and it is recommended that comparative controlled trials are necessary to judge the place of this drug in the management of advanced prostatic cancer.
摘要
30例雌激素抵抗性前列腺癌患者接受了磷酸雌莫司汀（癌腺治）治疗。27%患者出现部分客观缓解，33%有主观缓解。用于定义缓解的术语受到质疑，建议进行对照比较试验以判断该药物在晚期前列腺癌治疗中的地位。
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