Department of Mathematical and Computer Science, Physical Sciences and Earth Sciences, University of Messina, Messina, Italy.
BeSep s.r.l., c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy.
J Chromatogr A. 2021 Jul 5;1648:462191. doi: 10.1016/j.chroma.2021.462191. Epub 2021 Apr 29.
Consumers are daily exposed to a range of mineral oil hydrocarbons via food consumption. Major sources of MOH in food are packaging and additives, processing aids, and lubricants. In 2019, an EU guidance was released covering specific directions for sampling and analysis of mineral oil saturated hydrocarbons (MOSH) and mineral oil aromatic hydrocarbons (MOAH) in food and food contact materials within the frame of Recommendation (EU) 2017/84 for the monitoring of mineral oils. The parameters required by the guide are increasingly stringent, and coping with this type of analysis is now very challenging. It is within such a context that the present research is confined, inasmuch that it is focused on the construction of a low-cost, lab-made Y-interface for liquid-gas chromatography coupling used for the determination of MOSH and MOAH in foodstuffs. The response ratios of alkanes comprised between C and C were measured and were comprised between 0.9 and 1.1, with a maximum coefficient of variation of 4% (n = 5). Intermediate precision was evaluated for the fat/oil category during a period of 48 days obtaining a value of 10%. Qualitative and quantitative analysis of both MOSH and MOAH were performed in a single run and in a fully-automated manner. Seventeen different foods were analyzed in order to cover the categories reported in the EU guide. Saturated hydrocarbon contamination was detected only in a few samples (in the range 1-153 ppm); MOAH contamination was found only in one sample (sunflower oil: 15 ppm).
消费者每天通过食物摄入接触到一系列矿物油碳氢化合物。食物中 MOH 的主要来源是包装和添加剂、加工助剂和润滑剂。2019 年，欧盟发布了一项指导意见，涵盖了在建议（EU）2017/84 框架内对食品和食品接触材料中的矿物油饱和烃（MOSH）和矿物油芳烃（MOAH）进行采样和分析的具体方向。该指南中规定的参数越来越严格，应对这种类型的分析现在极具挑战性。正是在这种背景下，本研究才得以进行，主要是为了构建一种低成本的实验室制造的 Y 接口，用于液体-气体色谱耦联，用于测定食品中的 MOSH 和 MOAH。测量了介于 C 和 C 之间的烷烃的响应比，其值介于 0.9 和 1.1 之间，最大变异系数为 4%（n=5）。在 48 天的时间内，对脂肪/油类别进行了中间精密度评估，得到了 10%的值。以单步和全自动方式进行了 MOSH 和 MOAH 的定性和定量分析。为了涵盖欧盟指南中报告的类别，分析了 17 种不同的食物。仅在少数样本中检测到饱和烃污染（范围为 1-153 ppm）；仅在一个样本中发现了 MOAH 污染（葵花籽油：15 ppm）。
