Cedars-Sinai Medical Center - Pulmonary & Critical Care Medicine, Los Angeles, California, United States.
Department of Medicine, Division of Pulmonary & Critical Care Medicine, Cedars-Sinai Medical Center - Venous Thromboembolism and Pulmonary Vascular Disease Research Program, Los Angeles, California, United States.
Postgrad Med. 2021 Aug;133(sup1):64-70. doi: 10.1080/00325481.2021.1931370. Epub 2021 Jun 14.
The diagnosis of pulmonary embolism (PE) is often made more challenging by the presence of diseases that can mimic thromboembolic disease. There is no specific or sensitive constellation of clinical signs or symptoms that can be used to diagnose PE. Ventilation/perfusion scans can have false-positive findings related to mediastinal conditions that can compress the pulmonary arteries, and pulmonary hemorrhage can resemble PE on V/Q scanning with potentially devastating consequences if anticoagulation is started. CT-scan related issues l eading to potential false-positive diagnoses range from inadequate imaging technique, to systemic-pulmonary shunting, to non-thrombotic occlusion of pulmonary arteries by tumor, septic emboli, and emboli of fat, air, and foreign material, as well as vasculitic processes. Careful assessment of the patient and consideration of these potential mimickers is imperative to correct diagnosis of this potentially life-threatening condition.
肺栓塞(PE)的诊断常常因存在可模拟血栓栓塞性疾病的疾病而变得更加具有挑战性。没有特定的或敏感的临床体征或症状组合可用于诊断 PE。通气/灌注扫描可能存在与纵隔条件相关的假阳性发现,这些条件可能会压迫肺动脉,而肺出血在 V/Q 扫描上可能类似于 PE,如果开始抗凝治疗,可能会产生潜在的灾难性后果。与潜在假阳性诊断相关的 CT 扫描相关问题包括成像技术不足、体肺分流、肿瘤、感染性栓子、脂肪栓子、空气栓子和异物栓子以及血管炎过程导致的非血栓性肺动脉闭塞。仔细评估患者并考虑这些潜在的类似物对于正确诊断这种潜在的危及生命的疾病至关重要。