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比利时结节病患者的临床特征。

Clinical characteristics of sarcoidosis patients in Belgium.

机构信息

Department of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.

Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, Leuven, Belgium.

出版信息

Acta Clin Belg. 2022 Apr;77(2):247-254. doi: 10.1080/17843286.2020.1821493. Epub 2020 Sep 16.

Abstract

BACKGROUND

Sarcoidosis is a non-caseating granulomatous disease, mostly affecting previously healthy persons in their fourth and fifth decade. In Belgium, there is a paucity of epidemiological data concerning sarcoidosis and it is unknown to what respect national data on sarcoidosis relates to the global epidemiology of the disease.

OBJECTIVES

In this cohort study we describe the patient population in an academic center of reference, serving both as a regional care center and a center for a tertiary referral.

METHODS

We collected epidemiological data among 234 consecutive patients consulting the outpatient sarcoidosis clinic during a two-year time period. We manually explored the electronic patient file for data retrieval.

RESULTS

Out of the 234 patients, 140 are male (60%) and 94 are female (40%) patients. Forced vital capacity showed a median decline of 2% during follow-up, whereas median diffusion capacity increased with 4% over the same period of time. Within our study cohort, we observed a preponderance in employment as construction workers (14%), the chemical industry (6%) and in the metal processing industry (6%).

CONCLUSION

The current study reports on epidemiological findings among the largest cohort of sarcoidosis patients in Belgium published to date.

UNLABELLED

[Figure: see text].

摘要

背景

结节病是一种非干酪样肉芽肿性疾病,主要影响第四和第五个十年的既往健康人群。在比利时,结节病的流行病学数据很少,尚不清楚国家有关结节病的数据在多大程度上与该疾病的全球流行病学相关。

目的

在这项队列研究中,我们描述了一家学术参考中心的患者人群,该中心既是区域护理中心,也是三级转诊中心。

方法

我们在两年的时间内收集了 234 例连续就诊于门诊结节病诊所的患者的流行病学数据。我们手动探索电子患者档案以检索数据。

结果

在 234 例患者中,140 例为男性(60%),94 例为女性(40%)。在随访期间,用力肺活量中位数下降了 2%,而弥散能力中位数在此期间增加了 4%。在我们的研究队列中,我们观察到从事建筑工人(14%)、化学工业(6%)和金属加工业(6%)的人数居多。

结论

目前的研究报告了迄今为止在比利时发表的最大结节病患者队列的流行病学发现。

未注明

[图:见正文]。

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