Brazhnik E S, Vinogradova O S
Zh Vyssh Nerv Deiat Im I P Pavlova. 1988 Mar-Apr;38(2):323-32.
Medial septal-diagonal band (MS-DB) units were examined extracellularly in chronic rabbits under two experimental conditions: 1) in an intact septum, under anaesthetic doses of pentobarbital (40 mg/kg, i.v.); 2) in a basally undercut septum of unanaesthetized rabbits. The background rhythmic burst activity was undistinguishable in both states. Low-frequency electric stimulation of afferent inputs (MFB, CA1, LS) led to entrainment of the theta-cycles. The upper limit of following was almost normal in the undercut septum, but was strongly reduced under pentobarbital. In units with the driving "by pause", the duration of the initial silent period under pentobarbital was increased almost twofold but in the basally undercut septum it was the same as in the normal state. Some MS-DB units with weak or absent theta-modulation reacted to stimulation by stimulus-locked single spike discharges which followed up to high frequencies in both conditions.
在两种实验条件下，对慢性家兔的内侧隔区 - 斜角带（MS - DB）神经元进行细胞外记录：1）在完整隔区，静脉注射麻醉剂量的戊巴比妥（40mg/kg）；2）在未麻醉家兔的基底切除隔区。两种状态下背景节律性爆发活动无明显差异。对传入输入（内侧前脑束、海马CA1区、外侧隔区）进行低频电刺激可导致θ节律的同步化。在切除隔区，跟随的上限几乎正常，但在戊巴比妥作用下则显著降低。在具有“暂停驱动”的神经元中，戊巴比妥作用下初始静息期的持续时间增加近两倍，但在基底切除隔区与正常状态相同。一些θ调制较弱或无θ调制的MS - DB神经元对刺激的反应是刺激锁定的单个动作电位发放，在两种条件下均可跟随至高频。
