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拥有更多双酚 A 的驱动因素。

Drivers of owning more BPA.

机构信息

Department of Animal Science & Technology and BET Research Institute, Chung-Ang University, Anseong, Gyeonggi-do 17546, Republic of Korea.

Department of Animal Science & Technology and BET Research Institute, Chung-Ang University, Anseong, Gyeonggi-do 17546, Republic of Korea.

出版信息

J Hazard Mater. 2021 Sep 5;417:126076. doi: 10.1016/j.jhazmat.2021.126076. Epub 2021 May 11.

Abstract

Bisphenol A (BPA) is a ubiquitous environmental toxin worldwide. Despite the many studies documenting the toxicity of this substance, it remains a popular choice for consumer products. The internet, magazine articles, and newspaper reports are replete with tips on how to avoid BPA exposure, which mostly spread contradictory and often unscientific information. Therefore, based on a comprehensive search of the available biomedical literature, we summarized several confounding factors that may be directly or indirectly related to human BPA exposure. We found that the unique properties of BPA materials (i.e. low cost, light-weight, resistance to corrosion, and water/air-tightness), lack of personal health and hygiene education, fear of BPA-substitutes (with yet unknown risks), inappropriate production, processing, and marketing of materials containing BPA, as well as the state of regulatory guidance are influencing the increased exposure to BPA. Besides, we detailed the disparities between scientifically derived safe dosages of BPA and those designated as "safe" by government regulatory agencies. Therefore, in addition to providing a current assessment of the states of academic research, government policies, and consumer behaviors, we make several reasonable and actionable recommendations for limiting human exposure to BPA through improved labeling, science-based dosage limits, and public awareness campaigns.

摘要

双酚 A(BPA)是一种在全球范围内普遍存在的环境毒素。尽管有许多研究记录了这种物质的毒性,但它仍然是消费产品的热门选择。互联网、杂志文章和报纸报道充斥着如何避免 BPA 暴露的提示,但这些提示大多传播相互矛盾且往往不科学的信息。因此,我们基于对现有生物医学文献的全面搜索,总结了几个可能直接或间接与人类 BPA 暴露有关的混杂因素。我们发现 BPA 材料的独特特性(即低成本、重量轻、耐腐蚀、防水/气密封性)、缺乏个人健康和卫生教育、对 BPA 替代品的恐惧(具有未知风险)、材料的不当生产、加工和营销含有 BPA,以及监管指导的状态都影响着 BPA 的暴露增加。此外,我们详细说明了科学推导的 BPA 安全剂量与政府监管机构指定的“安全”剂量之间的差异。因此,除了提供对学术研究、政府政策和消费者行为现状的评估外,我们还通过改进标签、基于科学的剂量限制和公众意识运动,提出了一些合理且可操作的建议,以限制人类接触 BPA。

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