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高级执业药师2型糖尿病管理项目的影响:一项试点研究。

Impact of an Advanced Practice Pharmacist Type 2 Diabetes Management Program: A Pilot Study.

作者信息

Lewis Jelena, Nguyen Tiffany, Althobaiti Hana, Alsheikh Mona Y, Borsari Brad, Cooper Suzanne, Kim David S, Seoane-Vazquez Enrique

机构信息

Chapman University School of Pharmacy.

College of Pharmacy, Taif University, Saudi Arabia.

出版信息

Innov Pharm. 2019 Oct 31;10(4). doi: 10.24926/iip.v10i4.2237. eCollection 2019.

Abstract

BACKGROUND

The purpose of this study was to describe the impact of an Advanced Practice Pharmacist (APh) on lowering hemoglobin A1c (HbA1c) in patients with type 2 diabetes within a patient centered medical home (PCMH) and to classify the types of therapeutic decisions made by the APh.

METHODS

This was a retrospective study using data from electronic health records. The study evaluated a partnership between Chapman University School of Pharmacy and Providence St. Joseph Heritage Healthcare that provided diabetes management by an Advanced Practice Pharmacist in a PCMH under a collaborative practice agreement. Change in the HbA1c was the primary endpoint assessed in this study. The type of therapeutic decisions made by the APh were also evaluated. Descriptive analysis and Wilcoxon signed ranktest were used to analyze data.

RESULTS

The study included 35 patients with diagnosis of type 2 diabetes mellitus managed by an APh from May 2017 to December 2017. Most of the patients were 60-79 years old (68.5%), 45.7% were female, and 45.7% were of Hispanic/Latino ethnicity. The average HbA1cwas 8.8%±1.4% (range=6.0%-12.4%) and 7.5%±1.4% (range=5.5%-12.4%) at the initial and final APh visit, respectively (p<0.0001). Therapeutic decisions made by the APh included drug dose increase (35.5% of visits), drug added (16.4%), drug dose decrease (6.4%), drug switch (5.5%), and drug discontinuation (1.8%).

CONCLUSION

The Advanced Practice Pharmacist's interventions had a significant positive impact on lowering HbA1c in patients with type 2 diabetes mellitus in a PCMH. The most common therapeutic decisions made by the APh included drug dose increase and adding a new drug.

摘要

背景

本研究的目的是描述高级执业药师(APh)对以患者为中心的医疗之家(PCMH)中2型糖尿病患者降低糖化血红蛋白(HbA1c)的影响,并对APh做出的治疗决策类型进行分类。

方法

这是一项使用电子健康记录数据的回顾性研究。该研究评估了查普曼大学药学院与普罗维登斯圣约瑟夫传统医疗保健公司之间的合作关系,该合作关系根据合作实践协议在PCMH中由高级执业药师提供糖尿病管理。HbA1c的变化是本研究评估的主要终点。还评估了APh做出的治疗决策类型。使用描述性分析和Wilcoxon符号秩检验来分析数据。

结果

该研究纳入了2017年5月至2017年12月由APh管理的35例2型糖尿病患者。大多数患者年龄在60 - 79岁之间(68.5%),45.7%为女性,45.7%为西班牙裔/拉丁裔。初次和末次APh就诊时的平均HbA1c分别为8.8%±1.4%(范围 = 6.0% - 12.4%)和7.5%±1.4%(范围 = 5.5% - 12.4%)(p<0.0001)。APh做出的治疗决策包括增加药物剂量(就诊次数的35.5%)、添加药物(16.4%)、减少药物剂量(6.4%)、更换药物(5.5%)和停药(1.8%)。

结论

在PCMH中,高级执业药师的干预对降低2型糖尿病患者的HbA1c有显著的积极影响。APh做出的最常见治疗决策包括增加药物剂量和添加新药。

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