Department of Dermatology, Al Azhar University, Cairo, Egypt.
Department of Dermatology, National Research Centre, Cairo, Egypt.
J Cosmet Dermatol. 2022 Apr;21(4):1547-1553. doi: 10.1111/jocd.14240. Epub 2021 Jun 1.
Acrochordons (fibroepithelial polyps, skin tags, papillomas) are common benign neoplasms of the skin.
To identify the prevalence of colonic polyps among patients presenting with skin tags and to determine a useful criteria for screening with colonoscopy.
Two hundred patients who fulfilled the selection criteria underwent physical, biochemical evaluation (fasting blood sugar (FBS), body mass index (BMI) calculation, occult blood in stool), and histopathological examination of the skin tags. Colonoscopy was performed in patients with positive blood in stool, and any polyps identified were resected or biopsied.
Occult blood in stool was insignificantly detected in 12 (6%) of the 200 subjects (p < 0.001), and they were referred for colonoscopy. A prevalence rate of 3.5% was reported, and of twelve colonoscopies performed, three patients were polyp-free, two were diagnosed with ulcerative colitis (UC), and seven patients were diagnosed with polyps that were removed and/or biopsied (p = 0.421). Of the seven polyps, three were hemorrhoidal polyps and the four other polyps were adenomatous polyps (villous adenoma).
The mere presence of skin tags does not significantly correlate with existence of colonic polyps and does not justify screening colonoscopy unless other metabolic, GIT, and biochemical markers are identified.
皮赘(纤维上皮性息肉、皮肤标签、乳头瘤)是常见的皮肤良性肿瘤。
确定患有皮肤标签的患者中结肠息肉的患病率,并确定用于结肠镜检查筛查的有用标准。
符合选择标准的 200 名患者接受了体格检查、生化评估(空腹血糖(FBS)、体重指数(BMI)计算、粪便潜血)和皮肤标签的组织病理学检查。对粪便潜血阳性的患者进行结肠镜检查,并切除或活检任何发现的息肉。
200 名患者中,有 12 名(6%)患者粪便潜血检测不明显(p<0.001),并被转诊进行结肠镜检查。报告的患病率为 3.5%,12 次结肠镜检查中,3 名患者无息肉,2 名被诊断为溃疡性结肠炎(UC),7 名被诊断为息肉,这些息肉被切除和/或活检(p=0.421)。在这 7 个息肉中,3 个是痔性息肉,另外 4 个是腺瘤性息肉(绒毛状腺瘤)。
仅仅存在皮肤标签与结肠息肉的存在没有显著相关性,除非发现其他代谢、胃肠道和生化标志物,否则不支持进行结肠镜检查筛查。