[非苯并咪唑类药物治疗棘球蚴病的研究进展]
[Progress of researches on the development of non-benzimidazoles for the treatment of echinococcosis].
作者信息
Li S, Han X M, Guo Y M
机构信息
Graduate College of Qinghai University, Xining 810000, China.
Qinghai Provincial People's Hospital, China.
出版信息
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2020 Sep 1;33(2):213-217. doi: 10.16250/j.32.1374.2020119.
The long-term use of benzimidazoles for the treatment of echinococcosis may cause multiple adverse reactions and low compliance. A search for novel agents, as an alternative of benzimidazoles, is therefore of great significance for the treatment of echinococcosis. This review focuses on the progress of researches on non-benzimidazoles for the clinical treatment of echinococcosis, including anti-parasitic agents, anti-proliferative agents and plant extracts, so as to provide insights into the further development of non-benzimidazoles.
长期使用苯并咪唑治疗棘球蚴病可能会引起多种不良反应且依从性低。因此，寻找新型药物作为苯并咪唑的替代品对于棘球蚴病的治疗具有重要意义。本文综述聚焦于非苯并咪唑类药物用于棘球蚴病临床治疗的研究进展，包括抗寄生虫药物、抗增殖药物和植物提取物，以期为非苯并咪唑类药物的进一步研发提供思路。
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