肾移植后的弓形虫病。

Toxoplasmosis after renal transplantation.

作者信息

Herb H M, Jontofsohn R, Löffler H D, Heinze V

出版信息

Clin Nephrol. 1977 Dec;8(6):529-32.

Abstract

Infection is the main cause of death following renal transplantation. In the literature 7 fatal cases of toxoplasmosis following renal transplantation have been described. In the present papers a case of reactivated toxoplasmosis is presented where the patient survived. Fortuitous withdrawal of therapy and transplant nephrectomy may have been responsible for the patient's survival. The problems of diagnosis of toxoplasmosis following renal transplantation are discussed. Early diagnosis is vitally important as successful treatment of toxoplasmosis with pyrimethamine and sulfonamides in patients receiving immunosuppressive therapy has been reported. It is emphasised that reaction of toxoplasmosis should always be considered in patients with fever of unknown origin and cerebral symptoms.

摘要

感染是肾移植后死亡的主要原因。文献中已描述了7例肾移植后发生的致命性弓形虫病病例。本文报告了1例弓形虫病复发但患者存活的病例。偶然停药和移植肾切除术可能是患者存活的原因。文中讨论了肾移植后弓形虫病的诊断问题。早期诊断至关重要，因为已有报道称接受免疫抑制治疗的患者使用乙胺嘧啶和磺胺类药物成功治疗弓形虫病。强调对于不明原因发热和有脑部症状的患者应始终考虑弓形虫病的反应。