Institute of Nano Electronic Engineering, Universiti Malaysia Perlis (UniMAP), Kangar, Perlis, 01000, Malaysia.
Faculty of Chemical Engineering Technology, Universiti Malaysia Perlis (UniMAP), Arau, Perlis, 02600, Malaysia.
Biotechnol Appl Biochem. 2022 Jun;69(3):1199-1208. doi: 10.1002/bab.2196. Epub 2021 Jun 3.
Current developments in sensors and actuators are heralding a new era to facilitate things to happen effortlessly and efficiently with proper communication. On the other hand, Internet of Things (IoT) has been boomed up with er potential and occupies a wide range of disciplines. This study has choreographed to design of an algorithm and a smart data-processing scheme to implement the obtained data from the sensing system to transmit to the receivers. Technically, it is called "telediagnosis" and "remote digital monitoring," a revolution in the field of medicine and artificial intelligence. For the proof of concept, an algorithmic approach has been implemented for telediagnosis with one of the degenerative diseases, that is, Parkinson's disease. Using the data acquired from an improved interdigitated electrode, sensing surface was evaluated with the attained sensitivity of 100 fM (n = 3), and the limit of detection was calculated with the linear regression value coefficient. By the designed algorithm and data processing with the assistance of IoT, further validation was performed and attested the coordination. This proven concept can be ideally used with all sensing strategies for immediate telemedicine by end-to-end communications.
当前传感器和执行器的发展预示着一个新时代的到来，通过适当的通信，可以更轻松高效地完成各种事情。另一方面，物联网（IoT）具有巨大潜力，涵盖了广泛的学科领域。本研究旨在设计一种算法和智能数据处理方案，将传感系统获得的数据传输到接收器。从技术上讲，这被称为“远程诊断”和“远程数字监测”，是医学和人工智能领域的一场革命。为了验证概念，我们已经针对一种退行性疾病（即帕金森病）实施了远程诊断的算法方法。使用从改进的叉指电极获得的数据，对传感表面进行了评估，获得了 100 fM（n = 3）的灵敏度，并且通过线性回归值系数计算了检测限。通过设计的算法和物联网的辅助数据处理，进一步进行了验证并证实了协调。这个经过验证的概念可以与所有传感策略一起使用，通过端到端通信实现即时远程医疗。
